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Gynecologic Cancer

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June 10, 2021
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Adavosertib alone, in combination with olaparib effective in ovarian cancer subset

Adavosertib alone, in combination with olaparib effective in ovarian cancer subset

Adavosertib alone and in combination with olaparib demonstrated efficacy among women with poly(ADP-ribose) polymerase (PARP) inhibitor-resistant ovarian cancer, according to study results presented during the virtual ASCO Annual Meeting.

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June 04, 2021
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Adjuvant chemotherapy after chemoradiation fails to extend OS in cervical cancer subset

Adjuvant chemotherapy after chemoradiation fails to extend OS in cervical cancer subset

Adjuvant chemotherapy following chemoradiation did not prolong OS or PFS compared with chemoradiation alone among women with locally advanced cervical cancer, according to results of the randomized phase 3 OUTBACK study.

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May 24, 2021
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FDA grants breakthrough therapy designation to combination for recurrent ovarian cancer

FDA grants breakthrough therapy designation to combination for recurrent ovarian cancer

The FDA granted breakthrough therapy designation to VS-6766 with defactinib for treatment of recurrent low-grade serous ovarian cancer, according to the agents’ manufacturer.

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May 24, 2021
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Atezolizumab regimen fails to extend PFS in newly diagnosed ovarian cancer

Atezolizumab regimen fails to extend PFS in newly diagnosed ovarian cancer

The addition of atezolizumab to chemotherapy and bevacizumab failed to significantly prolong PFS for women with newly diagnosed stage III or stage IV epithelial ovarian cancer, according to a phase 3 study in Journal of Clinical Oncology.

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May 21, 2021
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Cervical cancer incidence declines as rates of other HPV-associated cancers rise

Cervical cancer incidence declines as rates of other HPV-associated cancers rise

Incidence of cervical cancer declined as rates of other HPV-associated cancers increased significantly in the U.S. from 2001 to 2017, according to a population-based study of trends presented during the virtual ASCO Annual Meeting.

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May 06, 2021
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FDA grants priority review to Keytruda-Lenvima combination for kidney, endometrial cancers

FDA grants priority review to Keytruda-Lenvima combination for kidney, endometrial cancers

The FDA granted priority review to pembrolizumab plus lenvatinib for treatment of advanced renal cell carcinoma and advanced endometrial carcinoma, according to the agents’ manufacturers.

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May 03, 2021
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Adavosertib monotherapy active in recurrent uterine serous carcinoma

Adavosertib monotherapy active in recurrent uterine serous carcinoma

Adavosertib demonstrated clinical activity among women with recurrent uterine serous carcinoma, according to results of a phase 2 study published in Journal of Clinical Oncology.

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April 23, 2021
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Clinical, neuropsychological factors influence chemotherapy-induced nausea severity

Clinical, neuropsychological factors influence chemotherapy-induced nausea severity

Chemotherapy-induced nausea remains a significant clinical problem, but severity varies based on multiple factors, according to results presented during the virtual Oncology Nursing Society Congress.

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April 23, 2021
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Researcher develops novel sensor for early detection of ovarian cancer

Researcher develops novel sensor for early detection of ovarian cancer

Mijin Kim, PhD, has been selected to receive a 2021 Marie-Josée Kravis Women in Science Endeavor fellowship grant for her work on a novel sensor technology designed for early detection of ovarian cancer.

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April 22, 2021
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FDA approves Jemperli for endometrial cancer subset

FDA approves Jemperli for endometrial cancer subset

The FDA granted accelerated approval to dostarlimab-gxly for treatment of certain women with endometrial cancer.

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