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Gray Matter

Clinical Guidance
Multiple Sclerosis
Overview

Pathophysiology

Pavan Bhargava, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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April 15, 2024
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Lower brain volumes found in patients with both MS and obstructive sleep apnea

Lower brain volumes found in patients with both MS and obstructive sleep apnea

DENVER — In adults with multiple sclerosis, obstructive sleep apnea increases brain atrophy independent of obesity, a common comorbidity, according to a poster at the American Academy of Neurology annual meeting.

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September 27, 2023
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White, gray matter MRI abnormalities linked to risk for late-onset epilepsy

White, gray matter MRI abnormalities linked to risk for late-onset epilepsy

PHILADELPHIA — In older adults, the presence of white and gray matter abnormalities on MRI is linked to greater risk for late-onset epilepsy, according to a poster presentation.

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February 08, 2023
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Disparities in adversity linked to differences in brain structure of Black, white children

Disparities in adversity linked to differences in brain structure of Black, white children

Black children on average undergo more family conflict, material hardship and traumatic events than white children, resulting in differences in gray matter volume in key brain regions and disorders such as PTSD, data show.

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November 12, 2021
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Reproductive history events in midlife women may offer protection against brain aging

Reproductive history events in midlife women may offer protection against brain aging

Reproductive history events indicating more estrogen exposure correlated with larger gray matter volume in midlife women, according to a study published in Neurology.

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May 18, 2021
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COVID-19 impacts gray matter volume, especially among those with fever, receipt of oxygen

COVID-19 impacts gray matter volume, especially among those with fever, receipt of oxygen

Patients with COVID-19 experienced changes in gray matter volume, especially those with fever and those who received oxygen therapy, according to findings from a multivariate, observational study published in Neurobiology of Stress.

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February 05, 2021
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Gray matter atrophy differs among MS phenotypes

Gray matter atrophy differs among MS phenotypes

Researchers who characterized components of gray matter atrophy in MS found patterns that varied by clinical phenotype, according to results published in Neurology.