Gout
Anakinra comparable to triamcinolone for reducing gout flare pain
Although anakinra is not superior to triamcinolone in affecting gout pain intensity over 24 to 72 hours, it is comparable in pain reduction and even favored in most secondary outcomes, according to data published in Arthritis & Rheumatology.
Film, television may reinforce stereotypes, misconceptions about gout
Contemporary films and television shows portray gout as a funny or embarrassing condition triggered by dietary indulgence, potentially reinforcing inaccurate beliefs about the disease, according to findings published in BMC Rheumatology.
COLCOT: Colchicine beneficial in patients with diabetes, recent MI
Patients with diabetes and recent MI had reduced risk for first and total CV events with colchicine compared with placebo, according to new data from the COLCOT trial.
DASH diet reduces serum urate, especially in those with hyperuricemia
The Dietary Approaches to Stop Hypertension — or DASH — diet successfully reduces serum urate, particularly among those with hyperuricemia, according to data published in Arthritis & Rheumatology.
Addressing obesity may prevent most incident gout cases in men
Avoiding obesity, alcohol consumption and diuretic use, while maintaining a DASH-style diet, may prevent most incident gout cases among men, according to data published in JAMA Network Open.
Colchicine prices remain high despite introduction of generics
Although the FDA-mandated exclusivity of colchicine ended and generics were introduced to the market, prices have remained high, according to research published in JAMA Internal Medicine.
Worldwide cases of musculoskeletal disorders exceed 1 billion, demand 'global response'
There were approximately 1.3 billion cases of musculoskeletal disorders worldwide in 2017, leading to 121,300 deaths and 138.7 million disability adjusted life years, according to findings published in Arthritis & Rheumatology.
Hmong patients with gout develop earlier, severe disease with worse renal function
Hmong patients with gout are on average 11 years younger, and demonstrate worse renal function, than non-Hmong patients with similar rates of comorbidities, according to data published in Arthritis Care & Research.
Pegloticase plus mycophenolate mofetil reduces antidrug antibodies, boosts efficacy in gout
Patients with uncontrolled gout treated with pegloticase and mycophenolate mofetil exhibited reduced probability of developing antibodies to pegloticase and improved response rates at 12 weeks, according to data presented at ACR 2020.