Gout

Patients with gout demonstrate an increased risk for COVID-19-related death, with a greater burden in those with female vs. male sex, according to data published in The Lancet Rheumatology.

There are still more questions than answers regarding post-acute COVID-19 syndrome, despite mounting evidence documenting its existence, according to researchers.

All around the world, gout prevalence is growing at an alarming pace, while gout treatment remains as “horribly mismanaged” as ever.

High adherence to healthy diet options found within the USDA’s 2020-2025 Dietary Guidelines for Americans, including the heart-healthy DASH or the Mediterranean diet, significantly reduces the risk for gout in women, according to data.

A more intensive serum urate target is difficult to achieve with oral urate-lowering therapy, compared with a standard target of 0.3 mmol/L, and fails to improve bone erosion scores in patients with erosive gout, according to a study.

In a meta-analysis of seven trials, colchicine was associated with reduced risk for MACE in patients with CAD who underwent PCI.

Patients with gout are 20% more likely to undergo lower extremity amputation versus those without gout, independent of comorbidities and other risk factors, according to data published in JAMA Network Open.

A semi-quantitative plain radiographic scoring method for assessing new bone formation in sclerosis and spur in gout is feasible, valid and reproducible, according to data published in Arthritis Research & Therapy.

Early reduction in high-sensitivity C-reactive protein is “not a good biomarker” for canakinumab’s protective impact on future gout flares, according to data published in Arthritis Care & Research.

Although excess adiposity and genetic predisposition are individually strongly linked to greater gout risk, both combined result in a higher risk than the sum of each, especially in women, according to data.