Glucocorticoid

Add-on low-dose prednisolone improves long-term disease activity and progression in senior patients with established rheumatoid arthritis, albeit with an increase in non-severe adverse events, according to data.

Most patients with systemic lupus erythematosus across a trio of anifrolumab trials demonstrated concordant outcomes on BILAG-based Composite Lupus Assessment and SLE Responder Index responses, according to data.

Rheumatologists should assess for PR3- and MPO-ANCA using a “high-quality antigen-specific assay” as the primary testing method for patients suspected of ANCA-associated vasculitis, according to updated EULAR recommendations.

Cumulative exposure to glucocorticoids appeared associated with risk for adrenal insufficiency among patients with severe asthma, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

Glucocorticoids are still one of the most commonly used treatments for rheumatoid arthritis, with an estimated up to 50% of patients with RA in the United States using them long-term as of 2021.

Glucocorticoids can do a lot of harm over time. In this episode, John Stone, MD, MPH, walks us through the Glucocorticoid Toxicity Index, a validated tool to measure steroid toxicity over time that we’ll be seeing more of in the future.

COVID-19 fears and complications are likely to persist far into the future for immunocompromised individuals, a speaker noted at the Basic and Clinical Immunology for the Busy Clinician symposium.

Although initially more expensive, a physical therapy course for knee osteoarthritis is more cost-effective after 1 year than a course of glucocorticoid injections, according to data published in JAMA Network Open.

In this video from ACR Convergence 2021, Kathryn Dao, MD, provided insight on the data from the GLORIA trial, which found that steroids improved disease activity “but at a cost.”

Weekly tocilizumab delays initial flare and reduces glucocorticoid exposure in patients with relapsing and new-onset giant cell arteritis, according to data published in Rheumatology.