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Glucocorticoid

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June 02, 2024
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Oral therapy cuts androstenedione levels for children with congenital adrenal hyperplasia

Oral therapy cuts androstenedione levels for children with congenital adrenal hyperplasia

BOSTON — Crinecerfont lowered androstenedione levels and allowed for lower glucocorticoid doses for children with classic congenital adrenal hyperplasia, according to findings from the CAHtalyst Pediatric phase 3 trial.

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June 01, 2024
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Oral nonsteroidal treatment ‘new paradigm’ for adults with congenital adrenal hyperplasia

Oral nonsteroidal treatment ‘new paradigm’ for adults with congenital adrenal hyperplasia

BOSTON — Adults with congenital adrenal hyperplasia receiving an oral nonsteroidal treatment saw a marked reduction in daily glucocorticoid dose at 24 weeks with maintenance of androgen control compared with placebo, researchers reported.

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May 17, 2024
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New joint guideline focuses on treatment of glucocorticoid-induced adrenal insufficiency

New joint guideline focuses on treatment of glucocorticoid-induced adrenal insufficiency

Glucocorticoid tapering, education and treatment of adrenal crisis are three of the main focuses of a new clinical practice guideline on glucocorticoid-induced adrenal insufficiency.

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February 01, 2024
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VIDEO: Complications associated with polymyalgia rheumatica

VIDEO: Complications associated with polymyalgia rheumatica

In this video, Sebastian E. Sattui, MD, MS, discusses complications that can arise in patients with polymyalgia rheumatica.

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February 01, 2024
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VIDEO: 'Exciting time' for therapeutic options in polymyalgia rheumatica

VIDEO: 'Exciting time' for therapeutic options in polymyalgia rheumatica

In this video, Sebastian E. Sattui, MD, MS, discusses currently available and emerging treatment options in polymyalgia rheumatica.

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February 01, 2024
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VIDEO: Challenges in diagnosing, managing polymyalgia rheumatica

VIDEO: Challenges in diagnosing, managing polymyalgia rheumatica

In this video, Sebastian E. Sattui, MD, MS, discusses challenges in making a polymyalgia rheumatica diagnosis.

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December 18, 2023
2 min read
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Sarilumab superior to placebo for achieving sustained remission in polymyalgia rheumatica

Sarilumab superior to placebo for achieving sustained remission in polymyalgia rheumatica

Among patients with polymyalgia rheumatica who relapse during glucocorticoid tapering, sarilumab is effective at enabling them achieve sustained remission and lowering cumulative glucocorticoid use, according to data.

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December 11, 2023
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Ceasing both immunosuppressants, glucocorticoids leads to IgG4-RD relapse in most patients

Ceasing both immunosuppressants, glucocorticoids leads to IgG4-RD relapse in most patients

SAN DIEGO — Maintaining immunosuppression with or without low-dose glucocorticoids is superior to withdrawing both therapies in preventing relapses in IgG4-related disease, according to data presented at ACR Convergence 2023.

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December 06, 2023
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FDA grants breakthrough therapy designation for oral congenital adrenal hyperplasia drug

FDA grants breakthrough therapy designation for oral congenital adrenal hyperplasia drug

The FDA granted breakthrough therapy designation for an oral non-glucocorticoid medication for the treatment of congenital adrenal hyperplasia, according to an industry press release.

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November 30, 2023
2 min read
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Small-dose, short-duration glucocorticoid use increases risk for cardiac events in RA

Small-dose, short-duration glucocorticoid use increases risk for cardiac events in RA

SAN DIEGO — Glucocorticoid doses as small as 5 mg per day, in durations as short as 30 days, and a use period as long as 1 year all increase the risk for major adverse cardiac events in rheumatoid arthritis, said a speaker here.

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