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Glioblastoma

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August 07, 2020
4 min read
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Algorithm identifies risk-stratifying glioblastoma tumor cells

An unsupervised, automated machine learning algorithm successfully identified glioblastoma tumor cells and stratified survival outcomes, according to study results published in eLife.

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July 23, 2020
1 min read
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Top in hem/onc: Enzastaurin, financial toxicity, burnout

The FDA recently granted fast track designation to enzastaurin for the treatment of newly diagnosed glioblastoma. It was the top story in hematology/oncology last week.

News
July 22, 2020
1 min read
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10 important updates for Glioblastoma Awareness Day

Today is Glioblastoma Awareness Day.

News
July 17, 2020
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FDA grants fast track status to enzastaurin for newly diagnosed glioblastoma

The FDA granted fast track designation to enzastaurin for the treatment of patients with newly diagnosed glioblastoma, according to a press release from the agent’s manufacturer.

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June 09, 2020
1 min read
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FDA grants fast track designation to vaccine-enhanced cell therapy for glioblastoma

The FDA granted fast track designation to TVI-Brain-1, an adoptive T cell therapy for the treatment of glioblastoma multiforme, according to the agent’s manufacturer.

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May 26, 2020
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Novel gamma-delta T-Cell therapy for treatment of patients with newly diagnosed glioblastoma

Phase 1, open-label, interventional trial of drug-resistant immunotherapy with activated, gene-modified gamma-delta T cells in patients with newly diagnosed glioblastoma multiforme receiving maintenance temozolomide chemotherapy

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May 26, 2020
3 min read
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Novel CAR-T uses scorpion toxin to target brain tumors

Chimeric antigen receptor T-cell therapies have demonstrated limited antitumor activity in glioblastoma. Although the therapies have been tolerable, response rates have been low and responses lack durability.

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May 26, 2020
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Intracerebral EGFR-vIII CAR T Cells for recurrent glioblastoma

Phase 1, open label, dose-escalation trial to determine the maximum tolerated dose of a novel, tumor-specific treatment with autologous EGFRvIII-CARs.

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May 15, 2020
2 min read
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Suicide risk higher within 1 year of brain cancer diagnosis

Risk for suicide appeared higher among individuals within the first year of a brain cancer diagnosis compared with the general population, according to a research letter published in JAMA Network Open.

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May 09, 2020
1 min read
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Seven important updates for National Brain Tumor Awareness Month

National Brain Tumor Awareness Month is commemorated in May.

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