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Glioblastoma

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October 18, 2023
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Novel gene therapy shows preliminary efficacy for glioblastoma

Novel gene therapy shows preliminary efficacy for glioblastoma

A novel oncolytic virus gene therapy extended survival among a small cohort of patients with high-grade glioblastoma, according to study results published in Nature.

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October 09, 2023
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Anti-CTLA-4 immune checkpoint inhibitor may hold promise for glioblastoma treatment

Anti-CTLA-4 immune checkpoint inhibitor may hold promise for glioblastoma treatment

Researchers at Salk Institute for Biological Studies have achieved promising results in early studies using an anti-CTLA-4 antibody for treatment of glioblastoma, the most common and deadliest form of brain cancer.

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September 19, 2023
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FDA grants fast track designation to leukemia, lymphoma and endometrial cancer therapies

FDA grants fast track designation to leukemia, lymphoma and endometrial cancer therapies

The FDA announced several regulatory actions.

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September 15, 2023
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FDA expands approval of Temodar to treat brain cancer

FDA expands approval of Temodar to treat brain cancer

The FDA expanded use of Temodar to include two new indications for the treatment of adults with anaplastic astrocytoma.

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August 22, 2023
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Partnership announces addition of novel cancer-killing biologic to glioblastoma trial

Partnership announces addition of novel cancer-killing biologic to  glioblastoma trial

A California-based nonprofit and a biotechnology firm announced the activation of novel biologic ADI-PEG 20 in the GBM AGILE platform trial, a study that evaluates therapies for individuals with newly diagnosed or recurring glioblastoma.

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August 11, 2023
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FDA approves diagnostic for GI stromal tumors, seeks more data for GVHD therapy

FDA approves diagnostic for GI stromal tumors, seeks more data for GVHD therapy

The FDA announced several regulatory actions the past few weeks.

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July 19, 2023
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Glioblastoma Awareness Day: Combination provides ‘notable’ survival benefit

Glioblastoma Awareness Day: Combination provides ‘notable’ survival benefit

Today is Glioblastoma Awareness Day.

News
May 31, 2023
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Oncolytic virus plus immunotherapy extends survival in recurrent glioblastoma

Oncolytic virus plus immunotherapy extends survival in recurrent glioblastoma

The combination of intratumoral DNX-2401 and pembrolizumab appeared safe and provided “notable survival benefits” for select patients with recurrent glioblastoma, according to a study published in Nature Medicine.

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May 14, 2023
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Brain Cancer Awareness Month: Vaccine confers benefit, AI identifies potential targets

Brain Cancer Awareness Month: Vaccine confers benefit, AI identifies potential targets

May is Brain Cancer Awareness Month.

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May 05, 2023
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Disulfiram and copper ‘should not be recommended’ for patients with recurrent glioblastoma

Disulfiram and copper ‘should not be recommended’ for patients with recurrent glioblastoma

The addition of disulfiram and copper to chemotherapy did not result in a significant survival benefit for patients with recurrent glioblastoma, according to data published in JAMA Network Open.

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