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Glioblastoma

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July 23, 2024
14 min read
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Early findings suggest CAR-T for solid tumors may advance beyond ‘very nascent stage’

Early findings suggest CAR-T for solid tumors may advance beyond ‘very nascent stage’

It’s only the beginning.

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May 29, 2024
4 min read
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mRNA vaccine reprograms immune system to attack glioblastoma

mRNA vaccine reprograms immune system to attack glioblastoma

An mRNA cancer vaccine developed at University of Florida may have the ability to reprogram the immune system against glioblastoma, findings of a first-in-human trial showed.

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May 18, 2024
1 min read
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Brain Tumor Awareness Month: Novel treatments exceed expectations, CAR-Ts show promise

Brain Tumor Awareness Month: Novel treatments exceed expectations, CAR-Ts show promise

May is Brain Tumor Awareness Month.

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March 27, 2024
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‘We were shocked’: CAR-T rapidly reduces size of brain tumors in phase 1 trial

‘We were shocked’: CAR-T rapidly reduces size of brain tumors in phase 1 trial

A novel bivalent-targeting, intrathecally delivered chimeric antigen receptor T-cell therapy decreased tumor size in patients with recurrent glioblastoma, according to results from a phase 1 study published in Nature Medicine.

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March 21, 2024
5 min read
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Microbubble-enhanced sonobiopsy could ‘revolutionize’ treatment of brain tumors

Microbubble-enhanced sonobiopsy could ‘revolutionize’ treatment of brain tumors

Focused ultrasound could provide clinicians a safer alternative in diagnosing, monitoring and treating patients with brain tumors compared with biopsy, according to findings published in npj Precision Oncology.

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March 14, 2024
4 min read
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Multi-engineered CAR-T confers significant, rapid reduction of aggressive brain tumor

Multi-engineered CAR-T confers significant, rapid reduction of aggressive brain tumor

A novel chimeric antigen receptor T-cell therapy produced significant tumor reductions in patients with glioblastoma, results from a phase 1 trial published in The New England Journal of Medicine showed.

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January 29, 2024
5 min read
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MRI-guided radiation with AI allows for real-time monitoring of glioblastoma treatment response

MRI-guided radiation with AI allows for real-time monitoring of glioblastoma treatment response

Researchers at Sylvester Comprehensive Cancer Center at University of Miami devised an MRI-guided radiation therapy technique using machine learning that may allow for real-time monitoring of glioblastoma treatment response.

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November 18, 2023
2 min read
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FDA grants priority review to therapy for relapsed leukemia, lymphoma

FDA grants priority review to therapy for relapsed leukemia, lymphoma

The FDA announced several regulatory actions.

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November 06, 2023
1 min read
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Small-molecule therapy fails to improve efficacy in brain cancer trial

Small-molecule therapy fails to improve efficacy in brain cancer trial

A small-molecule chemotherapeutic did not improve efficacy compared with standard therapies in adults with glioblastoma, according to the manufacturer.

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October 31, 2023
5 min read
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Devices implanted into brain tumors during surgery may guide treatment

Devices implanted into brain tumors during surgery may guide treatment

An implantable microdevice designed to test treatments in patients with gliomas during standard-of-care surgery has been easily and safely incorporated into surgical practice.

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