Giant Cell Arteritis
Moving away from ‘failed’ prednisone to IL-6 blockade in giant cell arteritis
No single sign, symptom adequate 'to rule in or rule out' giant cell arteritis
GCA, TAK likely react differently to tocilizumab, despite disease similarities
Elderly man presents with bilateral decreased vision

An 83-year-old man presented to the New England Eye Center with a 2-week history of decreased vision in both eyes. He felt like letters were “clumping together,” making it difficult to read. He also complained that the inferior half of his vision in the right eye was foggy. He denied any new headaches, jaw claudication, transient visual obscurations, scalp tenderness, recent weight loss or fatigue. He was experiencing new gait instability and poor coordination.
Greater cumulative glucocorticoids dose confers risk for hypertension
Giant Cell Arteritis Curbside Consults: Patient Presenting to the Emergency Department With New-Onset Visual Symptoms
3rd Annual Association of Women in Rheumatology National Conference: Immunology Bootcamp - Best Of!
Immune-mediated inflammatory diseases (IMIDs) are a group of clinically heterogeneous disorders, including rheumatoid arthritis, psoriasis, psoriatic arthritis, giant cell arteritis, systemic lupus erythematosus, and axial spondyloarthritis, that share a similar immunopathology. Recognizing the underlying immunopathological mechanisms of these disorders is essential for understanding how current and emerging therapies exert their effects. In this CME activity, recorded during the Association of Women in Rheumatology National Conference, experts in the field examine common signaling pathways in IMIDs, evaluate recent clinical evidence for available and emerging immune-based therapies that target these pathways, assess the utilization of biomarkers for the identification of patients with early inflammatory disease, and evaluate the mechanisms of cancer immunotherapies as they relate to both an antitumor response and the potential for autoimmunity.
Symptoms, imaging abnormalities differ in patients with TAK, GCA

Among patients with Takayasu’s and giant cell arteritis, certain symptoms, such as carotidynia, are more closely associated with vascular inflammation based on 18F-fluorodeoxyglucose positron emission tomography, or FDG-PET, while claudication and other symptoms are more linked to vascular damaged based on magnetic resonance angiography, according to data published in the Annals of the Rheumatic Diseases.