Geriatric Cancer

Researchers from Europe and the U.S. developed a hematologic toxicity score that can predict which patients are more likely to develop severe infections after chimeric antigen receptor T-cell therapy.

Older patients with cancer benefited from single-agent immune checkpoint inhibitors but had higher rates of adverse events and therapy discontinuation with increasing age, according to results of a retrospective study in JAMA Oncology.

Use of personalized interventions significantly reduced grade 3 or higher chemotherapy-related toxicity among patients with cancer aged 65 years or older, randomized trial results showed.

Older patients with late-stage non-small cell lung cancer appeared to benefit from immunotherapy, according to results presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer.

Older cancer survivors had a greater likelihood and faster rate of functional decline — including weak grip strength, slow gait speed and lower overall physical performance — than those without a cancer history, according to study results.

An advanced practice nurse-led clinic conducted via telehealth proved a safe approach for geriatric assessment implementation, according to study results presented at the virtual Oncology Nursing Society Congress.

A dose-adjusted lenalidomide regimen that included discontinuation of dexamethasone after 9 months appeared safe and led to similar outcomes as continuous lenalidomide plus dexamethasone among older patients with multiple myeloma.

Complete responses to idecabtagene vicleucel appeared consistent regardless of age among patients with relapsed or refractory multiple myeloma, according to study results presented at TCT Meetings Digital Experience.

Autologous hematopoietic stem cell transplant conferred favorable 2-year outcomes among older adults with multiple myeloma, according to study results presented at TCT Meetings Digital Experience.

Age has been identified as a risk factor for complications and toxicities related to various cancer treatments.