Gerd
Children, teens face 25% higher risk for adverse GI outcomes after COVID-19 infection
Children and adolescents with documented postacute COVID-19 syndrome experienced increased risk for gastrointestinal symptoms and disorders, according to a study published in JAMA Open Network.
Methylated DNA biomarker panel noninvasively detects esophageal cancer, precursors
A methylation biomarker panel paired with a minimally invasive sponge-capsule device identified Barrett’s esophagus, esophageal adenocarcinoma and high-grade dysplasia, according to a study published in American Journal of Gastroenterology.
Gastric bypass leads to greater long-term excess BMI loss than sleeve gastrectomy
Adults with obesity who underwent Roux-en-Y gastric bypass achieved a greater excess BMI loss at 10 years compared with those who underwent a laparoscopic sleeve gastrectomy, according to data published in JAMA Surgery.
COPD plus GERD, diabetes or osteoporosis raises odds for exacerbations, health care use
Having GERD, diabetes or osteoporosis in addition to COPD heightened the likelihood for exacerbations, ED visits and hospitalizations, according to results published in Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.
Upper GI mucosal damage, H. pylori infection may increase risk for Parkinson’s disease
The presence of mucosal damage on upper gastrointestinal endoscopy was associated with a 76% greater risk for developing Parkinson’s disease, underscoring the need for “increased vigilance” among these patients, according to a cohort study.
Exacerbation risk factors identified in patients with COPD, no recent exacerbations
Four variables, including chronic bronchitis and high symptom burden, heightened the rate of exacerbations among patients with COPD and no recent exacerbations, according to results published in Annals of the American Thoracic Society.
‘Aggressive’ treatment of GERD improves survival in systemic sclerosis with ILD
“Aggressive” combination therapy for gastroesophageal reflux disease improved survival among patients with systemic sclerosis and interstitial lung disease, according to data published in Arthritis Research & Therapy.
Probability-based screening for BE, esophageal cancer could reduce screening needs by 45%
Targeted screening of older adults with GERD and a 5% probability of Barrett’s esophagus or esophageal adenocarcinoma could “substantially decrease” the population to screen, while still detecting more than 70% of disease, data showed.
VIDEO: Lifestyle modifications must be ‘personalized to the patient’ in GERD management
WASHINGTON — In a Healio video exclusive, Carolyn Newberry, MD, discusses the importance of “personalized” lifestyle modifications, such as identifying dietary triggers and being mindful of meal-timing, for the management of GERD.
Vonoprazan reduces heartburn symptoms as early as day 1 in nonerosive reflux disease
WASHINGTON — Vonoprazan effectively relieved heartburn symptoms in patients with nonerosive reflux disease as early as day 1 of treatment, with results persisting after a 4-week placebo-controlled period through 20 weeks, according to data.