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Genitourinary Cancer

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October 21, 2021
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Neuroendocrine tumors require individualized treatment approach

Neuroendocrine tumors require individualized treatment approach

Patients with neuroendocrine tumors are at greater risk for cancer-associated death compared with death due to other causes; however, mortality rates vary according to tumor site.

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October 11, 2021
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Black patients less likely to meet eligibility criteria for pancreatic cancer trials

Black patients less likely to meet eligibility criteria for pancreatic cancer trials

Standard eligibility criteria for pancreatic cancer clinical trials differentially exclude Black patients from participation, according to results a simulated screening process.

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October 11, 2021
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FDA places clinical hold on Allogene’s allogeneic CAR-T trials

FDA places clinical hold on Allogene’s allogeneic CAR-T trials

The FDA placed a clinical hold on a series of clinical trials that use Allogene Therapeutics’ AlloCAR T chimeric antigen receptor T-cell therapies, according to a press release from the manufacturer.

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October 08, 2021
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Excluding race in kidney function estimates may impact cancer treatment for Black patients

Excluding race in kidney function estimates may impact cancer treatment for Black patients

Removing race from estimated glomerular filtration rate equations could result in more Black patients being excluded from anticancer therapy, thus negatively affecting outcomes, according to study results published in The Lancet Oncology.

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October 05, 2021
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Second COVID-19 vaccine dose equally effective in people with, without solid cancers

Second COVID-19 vaccine dose equally effective in people with, without solid cancers

Patients with solid tumor cancers sustained similar COVID-19 antibody levels as individuals without cancer 6 months after the second dose of the mRNA COVID-19 vaccine, according to study results published in Cancer Discovery.

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October 01, 2021
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Berzosertib regimen does not extend PFS in metastatic urothelial cancer

Berzosertib regimen does not extend PFS in metastatic urothelial cancer

The addition of berzosertib to cisplatin and gemcitabine did not extend PFS among patients with metastatic urothelial cancer, according to results of a randomized phase 2 trial.

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September 25, 2021
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Prostate Cancer Foundation names genitourinary oncologist president, CEO

Prostate Cancer Foundation names genitourinary oncologist president, CEO

The Prostate Cancer Foundation named Charles J. Ryan, MD, as its president and CEO.

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September 22, 2021
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FDA grants fast track designation to CAR macrophage cell therapy for HER2-positive tumors

FDA grants fast track designation to CAR macrophage cell therapy for HER2-positive tumors

The FDA granted fast track designation to CT-0508 for treatment of patients with solid tumors that overexpress human epidermal growth factor receptor 2.

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September 17, 2021
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Nivolumab-ipilimumab combination confers durable benefit in advanced renal cell carcinoma

Nivolumab-ipilimumab combination confers durable benefit in advanced renal cell carcinoma

First-line nivolumab plus ipilimumab conferred durable survival benefit compared with sunitinib for patients with advanced renal cell carcinoma, according to results of the randomized phase 3 CheckMate-214 trial.

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September 01, 2021
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FDA grants full approval to Keytruda for urothelial carcinoma subset

FDA grants full approval to Keytruda for urothelial carcinoma subset

The FDA granted full approval to pembrolizumab for first-line treatment of certain patients with advanced urothelial carcinoma, according to the agent’s manufacturer.

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