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Genetic Testing

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November 19, 2020
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Top in hem/onc: Robotic prostatectomy, FoundationOne Liquid CDx test

Top in hem/onc: Robotic prostatectomy, FoundationOne Liquid CDx test

A novel technique for robotic prostatectomy allowed men to regain continence early after prostate cancer surgery, according to a recent study. It was the top story in hematology/oncology last week.

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November 09, 2020
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FDA approves FoundationOne Liquid CDx as companion diagnostic for several cancer therapies

FDA approves FoundationOne Liquid CDx as companion diagnostic for several cancer therapies

The FDA approved the FoundationOne Liquid CDx test as a companion diagnostic device to help identify multiple additional biomarkers in cell-free DNA isolated from plasma, according to a press release from the agency.

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October 26, 2020
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FDA approves FoundationOne CDx test as companion diagnostic for Vitrakvi

FDA approves FoundationOne CDx test as companion diagnostic for Vitrakvi

The FDA approved the FoundationOne CDx test to help identify certain neurotrophic receptor tyrosine kinase gene fusions in patients with solid tumors eligible for treatment with larotrectinib, according to a press release from the agency.

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September 22, 2020
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Rapid bedside genetic testing enhances safety, efficacy of antiplatelet therapy

Rapid bedside genetic testing enhances safety, efficacy of antiplatelet therapy

The landmark TAILOR-PCI trial showed encouraging evidence for genotype-guided antiplatelet therapy.

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July 17, 2020
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New framework takes genetic testing guidelines for prostate cancer ‘a step further’

New framework takes genetic testing guidelines for prostate cancer ‘a step further’

All men with metastatic prostate cancer should undergo genetic testing to better inform decisions on precision medicine or clinical trial eligibility, according to recommendations developed at a multidisciplinary consensus conference.

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July 13, 2020
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Rare obesity disorders call for genetic testing, targeted therapies

Rare obesity disorders call for genetic testing, targeted therapies

Severe obesity starting early in life is a hallmark of rare genetic disorders of obesity. A genetic diagnosis can alleviate feelings of guilt or blame and lessen social stigma for youths with these disorders and their families.

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July 09, 2020
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CVD genetic testing in athletes may be viable when deep clinical factors fail to diagnose

CVD genetic testing in athletes may be viable when deep clinical factors fail to diagnose

In an Italian study of elite and amateur athletes with suspected inherited CVD, researchers demonstrated that the presence of more than three clinical markers was highly indicative of a positive diagnosis from genetic testing for CVD.

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June 15, 2020
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Genetic testing in NSCLC could increase benefits of targeted therapy

Among patients with non-small cell lung cancer who harbor MET exon 14 skipping mutations, or METex14+, savolitinib demonstrated tolerability and anti-tumor activity, according to findings from a phase 2 study presented at the virtual ASCO annual meeting.

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May 19, 2020
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TAILOR PCI

TAILOR PCI

Determine whether genetic testing identifies an antiplatelet therapy for patients undergoing PCI who do not tolerate clopidogrel well.

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April 17, 2020
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Obesity, lifestyle influence type 2 diabetes risk regardless of genetic factors

Obesity, lifestyle influence type 2 diabetes risk regardless of genetic factors

Adults with obesity and unfavorable lifestyle factors are more likely to develop type 2 diabetes during 15 years of follow-up than those without excess weight and favorable lifestyle factors, regardless of their genetic predisposition for the disease, according to findings published in Diabetologia.

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