Genetic Testing
Sharing genetic testing with patients of African ancestry can improve kidney outcomes
Disclosing apolipoprotein L1 genetic testing to patients of African ancestry can lead to those with high-risk genotypes reducing systolic blood pressure, increasing kidney disease screening and improving lifestyle habits, according to data.
Germline BRCA testing underused for women with ovarian cancer and commercial insurance
About one-third of women with commercial insurance underwent genetic testing for ovarian cancer between 2008 and 2018 despite unequivocal recommendations for universal testing, according to research in JAMA Network Open.
Hereditary predisposition seen in one-third of pediatric patients with a Wilms’ tumor
Among 126 children diagnosed with a Wilms’ tumor, 42 showed hereditary factors, according to data published in the Journal of Clinical Oncology.
Blood testing identifies preeclampsia, disease risks in pregnancy months before symptoms
Researchers predicted preeclampsia in 75% of cases and preterm birth at nearly the same rate by analyzing maternal, fetal and placental RNA circulating in the mother’s blood during pregnancy, according to a study published in Nature.
Evolution of genetic testing for breast cancer spurs questions about best criteria to use
Genetic testing for breast cancer has evolved substantially since its inception nearly 30 years ago, according to a speaker at Chemotherapy Foundation Symposium.
Combined genetic testing may improve cardiomyopathy and arrhythmia diagnosis, management
Genetic testing confirmed clinically relevant variants in 20% of patients suspected of having cardiomyopathy or an arrhythmia disorder, with 70% of positive diagnoses having clinical management implications, according to new research.
’We are failing Black women’: Experts urge action to reduce disparities in breast cancer
Black women have the highest mortality rate of all women with breast cancer in the U.S., with a significant number presenting at an earlier age of diagnosis and with more advanced-stage disease.
Cost, ease of use cited as primary barriers for genetic testing in CKD diagnosis
Older women with triple-negative breast cancer should undergo genetic testing
Genetic testing for hereditary cancer should be offered to all women aged older than 65 years with triple-negative or ER-negative breast cancer, according to study results published in Journal of Clinical Oncology.
BLOG: Genetic testing a promising option for keratoconus decision-making
We know from twin and familial studies that keratoconus has a genetic component. First-degree relatives of people with keratoconus have a 15- to 67-fold greater risk for keratoconus than the general population.