Genetic Testing

Women with breast cancer who tested positive for certain genetic mutations appeared more likely to receive distinct treatments, according to results of a population-based cohort study published in JAMA Oncology.

Regardless of polygenic risk score for CAD, lifetime risk for CVD varies greatly depending on exposure to elevated LDL and systolic BP, according to research presented at the virtual American College of Cardiology Scientific Session.

While not meeting a performance goal, genetic screening of patients with ACS or stable CAD after PCI to guide antiplatelet therapy choice numerically reduced serious adverse CV events, according to the results of the TAILOR PCI trial.

Postmenopausal women with breast cancer had a threefold higher prevalence of pathogenic variants in breast cancer-associated genes than their cancer-free counterparts, according to results of a case-control study published in JAMA.

In this Editorial, Jeff Balser, MD, PhD, President and CEO of Vanderbilt University Medical Center and Dean of Vanderbilt University School of Medicine, discusses the challenges of interpreting commercial genetic test results to patients and reviews tools that are being developed by researchers at Vanderbilt University Medical Center to help clinicians manage patients based on their genomic information.

Healio and Cardiology Today compiled a list of the most-read articles on updates in genetics and CVD published in 2019.

Black patients with hypertrophic cardiomyopathy were often diagnosed at a younger age and were less likely to carry a sarcomere mutation compared with white patients, according to a study published in JAMA Cardiology.

The Association of Community Cancer Centers presented its ACCC Innovator Awards to seven member programs.

The advent of direct-to-consumer genetic testing has brought a complex science into the realm of mainstream culture, with more and more consumers using these tools to determine their ancestry and ethnicity.

ATLANTA — Some progress has been made in increasing the knowledge and awareness of FH among general practitioners, cardiologists and other specialists, although more needs to be done to increase these efforts, according to a presentation at the FH Foundation’s FH Global Summit.