Genetic Susceptibility

Long-term exposure to air pollutants, including particulate matter, increases the risk for developing systemic lupus erythematosus, according to data published in Arthritis & Rheumatology.

Discovery of higher GSDMB expression in children with a genetic defect linked to asthma explains why they commonly experience viral infections and face an elevated risk for asthma, according to study results.

NEW ORLEANS — Causal artificial intelligence used to augment a polygenic risk score for CAD helped estimate how much individual patients must lower their LDL, systolic BP or both to overcome inherited risk for a major coronary event.

Adults with a genetic susceptibility to COVID-19 infection may have an increased risk for hypothyroidism, according to findings from a Mendelian randomization published in Thyroid.

Lipoprotein(a) may have a causal role in incident atrial fibrillation risk, independent of its effect on atherosclerotic CVD, according to an analysis of U.K. Biobank data.

An above average birth weight is associated with lower bone mineral density and higher fracture risk later in life, according to data published in the Journal of Bone and Mineral Research.

Researchers have identified eight psychiatric disorders that share a common genetic structure, according to study results published in Cell.

Liver cirrhosis, also known as the fourth and most advanced stage of fibrosis, can result from a variety of causes including nonalcoholic fatty liver disease and very often from alcohol-related liver disease — the lines of which can also be blurred.