Genetic Predisposition To Disease

The common consensus for some time has been that the prevalence of autoimmunity and autoimmune diseases has been on the rise.

Rare and common genetic variants contribute substantially to susceptibility to hypertrophic cardiomyopathy in the general population and can help improve risk prediction beyond clinical factors, researchers reported.

In Native Hawaiian individuals, Polynesian ancestry is associated with elevated risk for diabetes, HF and obesity, according to a genetic study published in PLOS Genetics.

Using genetic markers with metabolic risk factors can predict an individual patient’s risk for developing liver related events due to non-alcoholic fatty liver disease, according to a researcher at The Liver Meeting Digital Experience.

A person with obesity is nearly six times more likely to develop type 2 diabetes over a decade when compared with a person of normal weight, independent of lifestyle factors and genetic risk for the disease, according to study data presented at the European Association for the Study of Diabetes annual meeting.

In this video, Ali Poyan Mehr, MD, Regional Director of the Glomerular Disease Program at Kaiser Permanente Northern California, discusses the major risk factors for IgA nephropathy.