Genetic Marker

In 2010, results of the phase 2 BATTLE study demonstrated that choice of cancer therapy could be individualized based upon a patient’s tumor characteristics.

In a multiethnic genome study of response to diabetes drugs, researchers identified an African-ancestry genetic variant associated with favorable insulin response to metformin, according to a speaker.

Some genetic factors associated with reproductive aging are also predictive of the frequency of vasomotor symptoms, according to a study published in Menopause.

Complete immunohistochemistry diagnostics reduced the need for subsequent gene testing in patients with Lynch syndrome, according to research published in Clinical Gastroenterology and Hepatology.

Multi-gene panel testing in colorectal cancer led to significant detection of heritable gene mutations compared with guideline-based testing, according to research published in Clinical Gastroenterology and Hepatology.

Children with a high genetic risk for developing type 1 diabetes are at an increased risk for the disease if they have overweight or obesity from age 2 to 10 years, according to trial data published in Diabetologia.

A large study of patients with primary open-angle glaucoma identified 44 new gene loci linked to glaucoma and confirmed 83 previously reported gene loci, which may improve diagnosis and treatment of glaucoma using genetic information.

In Native Hawaiian individuals, Polynesian ancestry is associated with elevated risk for diabetes, HF and obesity, according to a genetic study published in PLOS Genetics.

Research published in Stroke indicated a causal association between smoking and risk for nontraumatic subarachnoid hemorrhage among individuals of European descent in Britain.

Black young adults with favorable molecular-risk acute myeloid leukemia had poorer survival outcomes than their white counterparts, according to study results presented at the virtual ASH Annual Meeting and Exposition.