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Genetic Marker

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July 23, 2021
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Molecular tumor testing transformative, yet 'under-optimized'

In 2010, results of the phase 2 BATTLE study demonstrated that choice of cancer therapy could be individualized based upon a patient’s tumor characteristics.

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June 27, 2021
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African ancestry-specific genetic variant may influence response to metformin

African ancestry-specific genetic variant may influence response to metformin

In a multiethnic genome study of response to diabetes drugs, researchers identified an African-ancestry genetic variant associated with favorable insulin response to metformin, according to a speaker.

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April 30, 2021
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Genetic variants predict vasomotor symptom frequency in menopause

Genetic variants predict vasomotor symptom frequency in menopause

Some genetic factors associated with reproductive aging are also predictive of the frequency of vasomotor symptoms, according to a study published in Menopause.

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April 29, 2021
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Complete genetic testing explains germline variants in Lynch syndrome

Complete genetic testing explains germline variants in Lynch syndrome

Complete immunohistochemistry diagnostics reduced the need for subsequent gene testing in patients with Lynch syndrome, according to research published in Clinical Gastroenterology and Hepatology.

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April 27, 2021
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Germline genetic testing finds heritable gene mutations in colorectal cancer

Multi-gene panel testing in colorectal cancer led to significant detection of heritable gene mutations compared with guideline-based testing, according to research published in Clinical Gastroenterology and Hepatology.

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April 16, 2021
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Overweight compounds likelihood of type 1 diabetes for children with high genetic risk

Overweight compounds likelihood of type 1 diabetes for children with high genetic risk

Children with a high genetic risk for developing type 1 diabetes are at an increased risk for the disease if they have overweight or obesity from age 2 to 10 years, according to trial data published in Diabetologia.

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March 05, 2021
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Researchers identify new gene loci linked to glaucoma

Researchers identify new gene loci linked to glaucoma

A large study of patients with primary open-angle glaucoma identified 44 new gene loci linked to glaucoma and confirmed 83 previously reported gene loci, which may improve diagnosis and treatment of glaucoma using genetic information.

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February 11, 2021
2 min read
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Genetics contributes to diabetes, HF, obesity risk in Native Hawaiian individuals

Genetics contributes to diabetes, HF, obesity risk in Native Hawaiian individuals

In Native Hawaiian individuals, Polynesian ancestry is associated with elevated risk for diabetes, HF and obesity, according to a genetic study published in PLOS Genetics.

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January 14, 2021
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Smoking may be linked to risk for subarachnoid hemorrhage

Smoking may be linked to risk for subarachnoid hemorrhage

Research published in Stroke indicated a causal association between smoking and risk for nontraumatic subarachnoid hemorrhage among individuals of European descent in Britain.

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December 04, 2020
4 min read
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Black race an independent predictor of poor survival among young adults with AML

Black race an independent predictor of poor survival among young adults with AML

Black young adults with favorable molecular-risk acute myeloid leukemia had poorer survival outcomes than their white counterparts, according to study results presented at the virtual ASH Annual Meeting and Exposition.

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