Gastric Bypass

Adults who underwent gastric bypass were more likely to discontinue and less likely to restart medications for hypertension, hyperlipidemia and diabetes than those who underwent sleeve gastrectomy, according to study findings.

Postmenopausal women who received a daily prebiotic supplement years after gastric bypass saw no change in calcium absorption compared with women who received placebo, though some differential responses were observed in the prebiotic group.

Data has indicated thiazolidinedione pioglitazone and GLP-1 receptor agonists improve beta-cell function in patients with diabetes, prompting a meeting presenter to suggest both drugs be used as first-line therapies for the disease.

Roux-en-Y gastric bypass surgery may be associated with greater weight loss, diabetes control and lower risk for major adverse cardiovascular events compared with sleeve gastrectomy, according to findings published in Diabetes Care.

Insulin sensitivity and beta cell function improved among patients with type 2 diabetes after 18% body weight loss by diet or gastric bypass, according to a study presented at Digestive Disease Week.

Changes in the human gut microbiome after sleeve gastrectomy contribute to the negative skeletal impact of bariatric surgery among adults with obesity, according to a speaker.

Adults with obesity and type 2 diabetes who underwent bariatric surgery or a low-calorie diet intervention experienced similar metabolic benefits, with no evident clinically important effects independent of weight loss, study data show.

For patients with type 2 diabetes and obesity, undergoing Roux-en-Y gastric bypass surgery led to greater remission rates of albuminuria and early stage chronic kidney disease compared with best medical care.

Adolescents and young adults with obesity who underwent sleeve gastrectomy experienced a reduction in bone mineral density measures in the year after surgery when compared with nonsurgical controls, but did not experience a decrease in bone strength despite significant weight loss, according to findings published in Bone.

Adolescents with type 2 diabetes and obesity may be at lower risk for developing diabetic kidney disease if they receive bariatric surgery compared with medical treatment alone for diabetes, according to findings published in Diabetes Care.