Functional Gastrointestinal Disorder

Anthony Lembo, MD, Director of Research for Cleveland Clinic's Digestive Disease & Surgery Institute, discusses the diagnostic process for patients presenting with constipation; approaching management of patients with IBS-C and CIC; treatment options and recent therapeutic advances; health disparities; and important challenges of care.

The PARALLAX trial of sacubitril/valsartan for HF with preserved ejection fraction met one of its two co-primary endpoints, showing a reduction in NT-proBNP, but no additional benefit on 6-minute walk distance and functional class.

Ischemic stroke in patients with COVID-19 conferred greater mortality and worse functional outcomes than stroke in patients without COVID-19, according to a report published in Stroke.

Within 3 months after acute ischemic stroke, current smokers are at greater risk for unfavorable functional outcomes than patients who quit smoking or never started, according to research published in Stroke.

More than 25% of adults in the United States, Canada and United Kingdom fit the Rome IV criteria for at least one of the six functional bowel disorders, according to study results.