Frontotemporal Dementia

In this week’s edition, women are less likely than men to return to work after large vessel occlusion stroke; cognitive impairment, headaches and CVD are more common in former college football players; veterans, providers support the addition of integrative medicine for chronic headaches; and more.

The FDA and European Commission have both granted orphan drug designation to AviadoBio for its new gene therapy to treat frontotemporal dementia, according to a company press release.

A collaboration between Mayo Clinic researchers and a team dedicated to researching frontotemporal dementia has identified neurofilament light as a useful biomarker for the disease.

In a systematic review and meta-analysis of 95 studies, researchers identified a global, age-standardized rate of young-onset dementia of 119 per 100,000 population, which is higher than previous estimates.

A validated clinical scale detected early behavioral change in frontotemporal dementia, according to study results presented at the Alzheimer’s Association International Conference.

The common frontotemporal dementia gene variations have different behavioral and neuropsychiatric disturbances and different trajectories through the course of the disease, according to study results published in JAMA Network Open.