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Fred Hutchinson

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October 10, 2019
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HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Phase 1 study to determine the safety and feasibility of using HERV-E TCR-transduced autologous T Cells in patients with metastatic clear-cell renal-cell carcinoma.

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October 10, 2019
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Hope vs Hype: Managing Patient Expectations for CAR T-Cell Therapy

Imagine a young adult male in his late 20s picks up his cell phone and calls his mother. Overtly emotional and on the verge of releasing a full-out flow of tears, the young man says to the voice at the other end of the line, “Mom, there’s hope.”

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October 10, 2019
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HA-1 T TCR T Cell Immunotherapy for the Treating of Patients with Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Phase 1 study of adoptive immunotherapy with CD8+ and CD4+ memory T cells transduced to express an HA-1-specific T cell receptor for children and adults with recurrent acute leukemia after allogeneic hematopoietic stem cell transplantation.

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October 10, 2019
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Cameron Turtle Receives Fred Hutch’s Endowed Chair for Immunotherapy

Cameron Turtle, MD, PhD, a pioneer in the field of chimeric antigen receptor T-cell therapy, has been honored as the inaugural recipient of the Anderson Family Endowed Chair for Immunotherapy at Fred Hutchinson Cancer Research Center.

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October 10, 2019
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Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

Phase 1 dose-escalation clinical trial to determine the phase 2 dose of autologous TIL 1383I TCR gene-modified T cells using a retrovirus for patients with advanced melanoma.

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October 09, 2019
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The Leukemia & Lymphoma Society awards $13.8 million for research into pediatric blood cancers

The Leukemia & Lymphoma Society awards $13.8 million for research into pediatric blood cancers

The Leukemia & Lymphoma Society awarded $13.8 million in new pediatric research grants designed to identify more effective and precise treatments for children with blood cancer.

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September 18, 2019
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Seattle Cancer Care Alliance opens its doors to share its cellular therapy experience

Seattle Cancer Care Alliance opens its doors to share its cellular therapy experience

The Seattle Cancer Care Alliance, the clinical care partner of the Fred Hutchinson Cancer Research Center, has been at the forefront of cellular therapies for cancer treatment since the field emerged. It was there where E. Donnall Thomas, MD, and his team pioneered the use of bone marrow transplant during the 1970s and SCCA’s position remains unchanged in the field of cellular therapies as its research and clinical staff have administered more CAR T-cell therapies to patients than any other facility in the world.

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September 12, 2019
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Human herpesvirus 6B linked to increased mortality among certain HSCT recipients

Human herpesvirus 6B linked to increased mortality among certain HSCT recipients

Detection of human herpesvirus 6B in bronchoalveolar lavage fluid appeared associated with higher risk for mortality among allogeneic hematopoietic stem cell transplant recipients with lower respiratory tract disease, according to results of a retrospective, single-center study published in Journal of Clinical Oncology.

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September 10, 2019
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Expense reimbursement model aims to ‘level playing field’ for clinical trial participation

Expense reimbursement model aims to ‘level playing field’ for clinical trial participation

Clinical trials, superficially speaking, might seem custom-made for low-income patients with cancer.

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September 09, 2019
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Patients lack understanding of genomic results in Lung-MAP study

Patients lack understanding of genomic results in Lung-MAP study

BARCELONA — Many participants in the Lung-MAP biomarker-driven clinical trial lacked understanding of genomic test results despite indicating they had adequate information on the benefits and risks of trial enrollment, according to study results presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer.

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