Frailty

Frailty among patients with systemic sclerosis significantly increases the risk for mortality by nearly 10-fold, but shows the potential to improve over time, according to data published in Clinical Rheumatology.

Frailty progression occurred at a faster rate among patients with COPD and preserved ratio impaired spirometry vs. those with normal spirometry, according to results published in CHEST.

WASHINGTON — In this video, Namrata Singh, MD, MSCI, highlights two posters from her team investigating associations between cancer and rheumatoid arthritis, led by “rising stars.”

Significant predictors of FVC and diffusion capacity of lung for carbon monoxide included frailty, low fat-free mass index and sarcopenia in patients with idiopathic pulmonary fibrosis, according to data published in Respiratory Research.

According to published results, the use of gabapentinoids may be associated with an increased risk of hip fractures in older, frail patients and patients with chronic kidney disease.

Treatment of obesity-related HF with preserved ejection fraction with semaglutide 2.4 mg improved body weight, physical function and HF symptoms regardless of the extent of patient frailty, a speaker reported.

For older adults with non-STEMI, routine coronary intervention was safe but did not lower risk for death from CV causes or nonfatal MI compared with medical therapy alone, according to new data from the SENIOR-RITA trial.

ATLANTA — A home-based exercise intervention with protein supplementation improved physical performance at 12 weeks for older patients with frailty who underwent transcatheter aortic valve replacement, according to the PERFORM-TAVR trial.

Results showed patients categorized as frail may be at risk for loosening, infection, instability, longer length of stay, readmission and increased costs after revision total knee arthroplasty vs. with patients without frailty.

Sleep disorders including insomnia, poor sleep quality and short and long sleep duration were associated with physical frailty among middle-aged and older patients with HIV, researchers found.