Fractional Flow Reserve

Healio and Cardiology Today have curated a list of the most-read headlines from TCT 2021.

PCI guided by quantitative flow ratio, a novel approach to estimate fractional flow reserve, was associated with lower rates of MACE at 1 year compared with PCI guided by angiography, according to results of the FAVOR III China trial.

In the FAME 3 trial, PCI guided by fractional flow reserve failed to meet noninferiority for reduction of MACCE at 1 year compared with CABG in patients with three-vessel CAD.

Adding fractional flow reserve assessment of all epicardial vessels at the time of diagnostic coronary angiography did not reduce costs or improve quality of life compared with angiography alone in patients with chest pain.

Fractional flow reserve-guided strategy vs. angiography-guided strategy for PCI in patients with STEMI and multivessel disease.

Among patients with STEMI who underwent complete revascularization, a fractional flow reserve-guided strategy did not improve outcomes compared with an angiography-guided strategy, according to results of the FLOWER-MI trial.

Prognostic value and therapeutic potential of flow and pressure measurements to assess coronary artery stenosis.

Among patients with coronary artery lesions, medically treated vessels with abnormal fractional flow reserve but intact coronary flow reserve did not have noninferior outcomes vs. vessels with normal FFR and coronary flow reserve.

Using coronary CTA for comprehensive anatomic interpretation was superior to functional imaging to determine fractional flow reserve, researchers found in the CREDENCE trial.

Available data have shown that CT-derived fractional flow reserve is effective in evaluating CAD and should be integrated into clinical practice, according to a researcher.