Folate Deficiency

Women with serum folate levels that were too low or too high during midpregnancy were more likely to have an infant born with congenital heart disease, with maternal vitamin B12 and homocysteine levels modulating risk, researchers reported.

Serum folate levels between 4.3 ng/mL and 8.2 ng/mL and greater were associated with a lower cardiovascular mortality risk among patients with rheumatoid arthritis, according to data published in JAMA Network Open.