Fluoroquinolones
Treating a corneal infiltrate in a non-contact lens wearer
There are a range of fortified and unfortified antibiotic options for corneal conditions.
Combination treatment for swimmer's ear safe, efficacious
Combining the corticosteroid fluocinolone acetonide with ciprofloxacin was safe and efficacious in treating swimmer’s ear, although it was not superior to treatment with either agent alone, according to a study published in JAMA Network Open.
Stewardship bundle ‘dramatically’ decreases fluoroquinolone use in UTIs
An antimicrobial stewardship bundle implemented at nearly two dozen urgent and primary care clinics in Florida resulted in a dramatic decrease in fluoroquinolone use for UTIs, researchers reported.
Macrolides, fluoroquinolones reduce risk for anti-drug antibodies in IBD treatment
Avoidance of cephalosporins and penicillin with beta-lactamase inhibitors during anti-TNF therapy reduced the risk for anti-drug antibodies among patients with inflammatory bowel disease, according to research published in Gut.
Third-generation fluroquinolones not linked to Achilles tendon ruptures
The use of third-generation fluoroquinolones — specifically, garenoxacin, moxifloxacin, pazufloxacin, prulifloxacin and sitafloxacin — was not associated with an increased risk for Achilles tendon ruptures, a study in Japan showed.
Treating diverticulitis with amoxicillin-clavulanate spares risks tied to fluoroquinolones
Outpatient diverticulitis treatment with amoxicillin-clavulanate was “just as effective” as treatment with a combination of metronidazole and a fluoroquinolone, a researcher told Healio Primary Care.
Studies dispute claim fluoroquinolones elevate risk for aortic aneurysm, aortic dissection
Older adults who received fluoroquinolones had a low risk for aortic aneurysm or aortic dissection, two studies published in JAMA Internal Medicine show.
Q&A: New model could improve antibiotic development
Although the current approach to incentivizing antibiotic development has led to the creation of effective treatments, the pipeline has collapsed numerous times, leaving clinicians stranded against increasingly resistant infections, according to an article published the Annals of Internal Medicine.
Use of high-risk antibiotics correlates with more hospital-associated CDI
Using high-risk antibiotics is an independent predictor of hospital-associated Clostridioides difficile infections, or HA CDIs, according to a study published in Infection Control & Hospital Epidemiology.