Estradiol

Higher serum estradiol levels in early pregnancy were associated with increased risk for preeclampsia, particularly after frozen embryo transfer cycles, researchers reported in Frontiers in Endocrinology.

Hormone therapy with transdermal estradiol may benefit bone and CV health and overall quality of life up to 20 years after hysterectomy, according to study results published in Menopause.

PHILADELPHIA — The number of women aged at least 50 years prescribed hormone therapy for menopause symptoms remains low, particularly for Hispanic women, despite good efficacy and safety, according to a presenter.

An intravaginal ring with combination estradiol and progesterone was safe and effective in treating vasomotor symptoms in postmenopausal women, according to phase 1/2 study results published in Menopause.

The FDA approved a generic version of estradiol gel to treat moderate to severe vasomotor symptoms.

ANI Pharmaceuticals received FDA approval for an abbreviated new drug application for estradiol gel, 0.1%, according to a company press release.

BALTIMORE — Elagolix plus add-back of estradiol and norethindrone improved bleeding and non-bleeding symptoms linked to uterine fibroids among premenopausal women, according to researchers at the ACOG Annual Clinical & Scientific Meeting.

The surgical approach was the strongest predictor of total costs for outpatient benign hysterectomy, recent data show.

Estradiol cream applied to the vulvar vestibule plus precoital silicone lubricant may offer an alternative to vaginal therapy for women with dyspareunia, according to a randomized pilot trial published in Menopause.

Adolescents seeking an abortion demonstrated comparable accuracy in estimating gestational duration as older age groups, according to a research letter published in JAMA Pediatrics.