Epinephrine

Cases of epinephrine administration for food-induced anaphylaxis in U.S. pediatric EDs increased 4% each year between 2007 and 2015, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

Elevated levels of stress hormones such as norepinephrine, epinephrine, dopamine and cortisol were associated with increased risk for hypertension, and high levels of cortisol was also linked to CV events, researchers reported.

As children with food allergies return to class this fall, families and their doctors need to work with teachers and school nurses to ensure safe learning environments, according to a presentation during the Global Food Allergy Summit.

Later timing of epinephrine administration in out-of-hospital cardiac arrest was associated with poorer chances of survival to discharge, regardless of presence of a shockable rhythm, but findings were not significant, researchers reported.

The Biden administration issued a temporary freeze on a final rule that would require community health centers to pass on 340B drug discounts for insulin and injectable epinephrine to low-income patients.

Epinephrine with a local anesthetic is safe and effective with no instances of digital necrosis or need for phentolamine reversal in patients undergoing “wide-awake” hand and upper extremity surgery, according published results.

Researchers have developed an at-home anaphylaxis management algorithm for patients who need emergency epinephrine treatment. Importantly, it may prevent unnecessary ED visits — a particularly helpful development given the risk that COVID-19 poses in health care settings.

The FDA issued an alert about EpiPen 0.3 mg auto-injectors, EpiPen Jr. 0.15 mg auto-injectors and authorized generic versions, stating that these products may have delayed or incorrect injections that could cause injury or death.

Today, 1 in 50 Americans is at risk for anaphylaxis — a severe allergic reaction that can lead to death. Several states have acted and allow epinephrine to be available in more places and to be administered by more individuals than in the past.

HOUSTON — Between 2006 to 2015, the number of children aged younger than 3 years who visited the ED for anaphylaxis increased, but the number of subsequent hospitalizations decreased, according to findings presented at the American College of Asthma, Allergy & Immunology Scientific Meeting.