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Eosinophilic Esophagitis

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October 25, 2022
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Dupixent bests placebo in clinical, histological outcomes in patients with EoE

Dupixent bests placebo in clinical, histological outcomes in patients with EoE

CHARLOTTE, N.C. — Dupilumab improved clinical, symptomatic, histologic and endoscopic outcomes among patients treated for eosinophilic esophagitis, according to study results presented at the ACG Annual Scientific Meeting.

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October 24, 2022
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VIDEO: Model accurately rules out likelihood of EoE, prevents ‘unnecessary biopsies’

VIDEO: Model accurately rules out likelihood of EoE, prevents ‘unnecessary biopsies’

CHARLOTTE, N.C. — In a Healio video exclusive, Amrit Kamboj, MD, a gastroenterologist at Mayo Clinic Rochester, reported a predictive model accurately identified patients’ likelihood of eosinophilic esophagitis.

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October 04, 2022
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Top news of September: Penicillin allergy de-labeling, hidden food allergies, more

Top news of September: Penicillin allergy de-labeling, hidden food allergies, more

Healio compiled the most-read news in allergy, asthma and immunology posted in September.

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October 03, 2022
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Distensibility index superior measure for fibrostenotic severity in children with EoE

Distensibility index superior measure for fibrostenotic severity in children with EoE

The distensibility index provides a superior metric for fibrostenotic severity vs. esophageal diameter alone in pediatric patients with eosinophilic esophagitis, according to research published in Clinical Gastroenterology and Hepatology.

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September 09, 2022
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Vitamin D supplementation mitigates inflammation in eosinophilic esophagitis

Vitamin D supplementation mitigates inflammation in eosinophilic esophagitis

Supplementation with vitamin D may alleviate allergic inflammation in the esophagus, whereas a deficiency in vitamin D may lead to a higher risk for eosinophilic esophagitis and other allergic states, according to a study published in Gut.

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August 09, 2022
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Household detergent exposure may be linked to eosinophilic esophagitis

Household detergent exposure may be linked to eosinophilic esophagitis

Sodium dodecyl sulfate, a common household detergent, decreased the integrity of the esophageal barrier, stimulated IL-33 production and promoted epithelial hyperplasia and tissue eosinophilia, according to a study published in Allergy.

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July 25, 2022
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Patients with eosinophilic esophagitis symptoms may benefit from gastric emptying studies

Patients with eosinophilic esophagitis symptoms may benefit from gastric emptying studies

Gastric emptying studies may benefit patients with persistent symptoms of eosinophilic esophagitis who do not respond to treatment, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

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July 18, 2022
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Dupilumab confers remission of eosinophilic esophagitis among young children

Dupilumab confers remission of eosinophilic esophagitis among young children

Children aged 1 to 11 years with eosinophilic esophagitis safely achieved histologic disease remission after 16 weeks of treatment with the fully human monoclonal antibody dupilumab, according to the results of a phase 3 trial.

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June 01, 2022
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Q&A: FDA approval of dupilumab for eosinophilic esophagitis a ‘victory for rare diseases’

Q&A: FDA approval of dupilumab for eosinophilic esophagitis a ‘victory for rare diseases’

The FDA has approved the use of dupilumab for treating eosinophilic esophagitis in adults and children aged 12 years and older, making it the first drug in the U.S. specifically indicated for this condition.

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May 27, 2022
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Top in GI: Gallstone disease and pancreatic cancer; new eosinophilic esophagitis drug

Top in GI: Gallstone disease and pancreatic cancer; new eosinophilic esophagitis drug

A presenter at Digestive Disease Week reported that gallstone disease may be a predictor of pancreatic cancer.

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