Eosinophil
Asthma status, phenotype impact risk for preterm birth, cesarean delivery
The risk for preterm birth, low birth weight and cesarean delivery was heightened among women who had asthma during delivery hospitalization, according to research published in The Journal of Allergy and Clinical Immunology: In Practice.
Q&A: Mepolizumab marks second biologic approved for COPD with eosinophilic phenotype
The FDA recently approved mepolizumab for treating adults with inadequately controlled COPD and an eosinophilic phenotype, marking the second biologic approved as an add-on maintenance treatment in this patient population.
FDA approves mepolizumab for COPD with eosinophilic phenotype
The FDA granted approval to mepolizumab for treating adults with inadequately controlled COPD and an eosinophilic phenotype, according to a GSK press release.
Elevated eosinophil counts associated with cardiovascular disease
SAN DIEGO — Patients with higher eosinophil counts experienced more cardiovascular disease, according to a poster presented at the 2025 American Academy of Allergy, Asthma & Immunology/World Allergy Organization Joint Congress.
Baseline factors impact odds for clinical remission with dupilumab in asthma
SAN DIEGO — Researchers found increased odds for clinical remission on dupilumab with high blood eosinophil and fractional exhaled nitric oxide levels in a moderate to severe asthma cohort, according to a poster presented here.
Indolent rhinovirus infections may predict asthma development in children with wheeze
BOSTON — Rhinovirus infections in children with a nascent type 2 inflammatory signature may be at greater risk for asthma, according to an abstract presented at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.
FDA to review mepolizumab for COPD with eosinophilic phenotype
The FDA has accepted to review a supplemental new drug application for mepolizumab, an anti-IL-5 biologic, for treating patients with COPD plus an eosinophilic phenotype, according to a GSK press release.
Benralizumab for eosinophilic asthma/COPD exacerbations ‘could be a game-changer’
Receiving a benralizumab injection during an acute asthma or COPD exacerbation with a blood eosinophil count of at least 300 cells/µL led to fewertreatment failures, according to results published in The Lancet Respiratory Medicine.
Mild to moderate asthma may include high FeNO, eosinophil counts
Patients with mild to moderate asthma and self-reported asthma control may have elevated levels of fractional exhaled nitric oxide and eosinophils, according to a poster presented at the European Respiratory Society International Congress.
E-cigarette use associated with lower eosinophil counts among patients with HIV
BOSTON — The impact of e-cigarette use on eosinophil and basophil counts may depend on HIV serostatus, according to a study presented at the CHEST Annual Meeting.