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Endocrine Therapy

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September 20, 2022
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Responses to neoadjuvant endocrine therapy for advanced breast cancer differ by race

Responses to neoadjuvant endocrine therapy for advanced breast cancer differ by race

Black women with advanced-stage hormone receptor-positive breast cancer experienced poor response to treatment with neoadjuvant endocrine therapy compared with white women with similar disease presentation, according to study results.

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September 02, 2022
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Longer time to initiate adjuvant endocrine therapy for breast cancer may worsen adherence

Longer time to initiate adjuvant endocrine therapy for breast cancer may worsen adherence

Medicaid-insured women diagnosed with primary hormone receptor-positive breast cancer had lower odds of short- and long-term adherence to adjuvant endocrine therapy if they had a longer time to initiation of the therapy.

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June 08, 2022
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Adjuvant chemotherapy plus endocrine therapy fails to increase OS in breast cancer subset

Adjuvant chemotherapy plus endocrine therapy fails to increase OS in breast cancer subset

CHICAGO — The addition of chemotherapy to endocrine therapy did not extend OS after surgery among older patients with ER-positive, HER2-negative breast cancer with a high tumor genomic grade index.

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February 01, 2022
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VIDEO: Expert highlights EGFR-mutated lung cancer treatment pipeline

VIDEO: Expert highlights <i>EGFR</i>-mutated lung cancer treatment pipeline

Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, spoke with Healio about treatments in the pipeline for EGFR-mutated lung cancer.

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December 26, 2021
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VIDEO: Ongoing trial examining olaparib, palbociclib and fulvestrant in BC subset

VIDEO: Ongoing trial examining olaparib, palbociclib and fulvestrant in BC subset

In this video, Payal Shah, MD, assistant professor of medicine at the hospital of the University of Pennsylvania, spoke with Healio about the ongoing HOPE trial.

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December 21, 2021
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VIDEO: ‘Surprising’ results from PALLAS trial presented at SABCS

VIDEO: &lsquo;Surprising&rsquo; results from PALLAS trial presented at SABCS

In this video, Angela DeMichele, MD, MSCE, co-leader of the Breast Cancer Research Program and director of the Breast Cancer Clinical Trials Unit at Penn Medicine, discusses results from the PALLAS trial assessing palbociclib in early breast cancer.

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December 16, 2021
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Palbociclib regimens extend survival for Black, Hispanic women with advanced breast cancer

Palbociclib regimens extend survival for Black, Hispanic women with advanced breast cancer

The addition of palbociclib to endocrine therapy prolonged survival for Black and Hispanic women with hormone receptor-positive, HER2-negative metastatic breast cancer, according to results presented at San Antonio Breast Cancer Symposium.

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December 13, 2021
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VIDEO: Study provides real-world data on treatment sequencing in breast cancer subset

VIDEO: Study provides real-world data on treatment sequencing in breast cancer subset

Megan Kruse, MD, a breast medical oncologist at Cleveland Clinic, spoke with Healio about results from her research on real-world sequential and non-sequential use of CDK4/6 inhibitors in a subset of breast cancer patients.

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July 28, 2021
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Prolonged adjuvant anastrozole confers no DFS benefit in postmenopausal breast cancer

Prolonged adjuvant anastrozole confers no DFS benefit in postmenopausal breast cancer

A longer duration of extended hormone therapy provided no benefit for postmenopausal women with hormone receptor-positive breast cancer who had received 5 years of adjuvant endocrine therapy, according to randomized phase 3 study results.

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July 21, 2021
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Palbociclib plus endocrine therapy does not lower QOL in BIPOC

Palbociclib plus endocrine therapy was not associated with lowered quality of life among Black, indigenous and people of color with HR-positive, HER2-negative advanced breast cancer, according to research presented at ASCO 2021.

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