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Dual Antiplatelet Therapy

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November 19, 2021
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STOPDAPT-2 ACS

STOPDAPT-2 ACS

DAPT for 1 months or 12 months in patients with ACS undergoing PCI with a cobalt-chromium everolimus-eluting stent (Xience family, Abbott Vascular).

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November 11, 2021
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Post-PCI, clopidogrel monotherapy after 1 month reduces bleeding risk vs. 12-month DAPT

Post-PCI, clopidogrel monotherapy after 1 month reduces bleeding risk vs. 12-month DAPT

In a pooled cohort of the two STOPDAPT-2 trials, among patients who underwent PCI, switching from dual antiplatelet therapy to clopidogrel monotherapy after 1 month reduced bleeding risk compared with 12-month DAPT.

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November 08, 2021
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Magnetically controlled capsule endoscopy detects GI injury from antiplatelet therapy

Magnetically controlled capsule endoscopy detects GI injury from antiplatelet therapy

Magnetically controlled capsule endoscopy identified gastrointestinal injury in a majority patients taking antiplatelet therapies following PCI and may represent a noninvasive alternative to standard upper GI endoscopy, a speaker reported.

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November 06, 2021
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Abbreviated DAPT beneficial after PCI in high-risk patients regardless of MI status

Abbreviated DAPT beneficial after PCI in high-risk patients regardless of MI status

In a subgroup analysis of MASTER-DAPT, regardless of whether patients had a history of MI, 1-month DAPT after PCI was noninferior to 3-month or longer DAPT for ischemic events and conferred a reduction in bleeding events.

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September 28, 2021
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Long-term ticagrelor monotherapy after PCI lowers bleeding risk in ACS vs. 1-year DAPT

Long-term ticagrelor monotherapy after PCI lowers bleeding risk in ACS vs. 1-year DAPT

Long-term ticagrelor monotherapy after PCI lowered risk for bleeding compared with 1-year dual antiplatelet therapy followed by 1-year aspirin monotherapy in patients with ACS, but not for those with CAD.

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September 21, 2021
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MASTER DAPT

MASTER DAPT

Dual antiplatelet therapy for 1 month vs. 3 or more months in patients at high bleeding risk who had PCI with a biodegradable-polymer sirolimus-eluting stent (Ultimaster, Terumo).

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September 02, 2021
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STOPDAPT-2 ACS trial inconclusive for 1- vs. 12-month DAPT after PCI and DES implantation

STOPDAPT-2 ACS trial inconclusive for 1- vs. 12-month DAPT after PCI and DES implantation

Despite fewer bleeding events, 1-month dual antiplatelet therapy with clopidogrel failed to prove noninferiority vs. 12-month DAPT after PCI and stent implantation for ACS, according to a presenter.

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August 28, 2021
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DAPT for 1 month after PCI safe, effective in patients at high bleeding risk: MASTER DAPT

DAPT for 1 month after PCI safe, effective in patients at high bleeding risk: MASTER DAPT

In patients at high bleeding risk, dual antiplatelet therapy for 1 month after PCI lowered bleeding rates and was noninferior for ischemic events compared with 3-month DAPT, according to results of the MASTER DAPT trial.

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June 28, 2021
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In high-risk patients, optimal medical therapy confers survival benefit after PCI, CABG

In high-risk patients, optimal medical therapy confers survival benefit after PCI, CABG

At 10 years, patients with three-vessel or left main disease who underwent PCI or CABG were more likely to survive if they were taking optimal medical therapy at 5 years, researchers reported.

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May 19, 2021
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EVOLVE Short DAPT

EVOLVE Short DAPT

DAPT for 3 months or 12 months after PCI with an everolimus-eluting stent (Synergy, Boston Scientific).

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