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Drug-Eluting Stent

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October 28, 2019
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BIODEGRADE: Cobalt-chromium DES noninferior to stainless steel DES for ACS

BIODEGRADE: Cobalt-chromium DES noninferior to stainless steel DES for ACS

SAN FRANCISCO — A cobalt-chromium drug-eluting stent was noninferior to a stainless steel DES in patients with ACS who were undergoing PCI, according to 18-month results from the BIODEGRADE trial presented at TCT 2019.

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October 25, 2019
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IVUS-XPL: In long lesions, IVUS-guided PCI retains superior outcomes at 5 years

IVUS-XPL: In long lesions, IVUS-guided PCI retains superior outcomes at 5 years

SAN FRANCISCO — Among patients who underwent PCI for long lesions, IVUS-based guidance was associated with better outcomes than angiography-based guidance at 5 years, according to new data from the IVUS-XPL trial presented at TCT 2019.

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October 19, 2019
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Pharmacotherapy highlights from TCT: TWILIGHT, Onyx ONE and more

Pharmacotherapy highlights from TCT: TWILIGHT, Onyx ONE and more

As drug-eluting stent technology has evolved, stent thrombosis has become less of a risk and the standard recommendation of 1 year of dual antiplatelet therapy after PCI is being challenged, especially for patients at high bleeding risk.

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October 09, 2019
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Another study finds no evidence of increased long-term mortality with paclitaxel-coated devices

Another study finds no evidence of increased long-term mortality with paclitaxel-coated devices

Patients who underwent endovascular revascularization with a paclitaxel-based drug-eluting device did not have an increased mortality risk over an 11-year follow-up period, according to a safety analysis published in the European Heart Journal.

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October 04, 2019
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BLADE-PCI: Novel liposomal alendronate fails in diabetes

BLADE-PCI: Novel liposomal alendronate fails in diabetes

SAN FRANCISCO — Intravenous administration of a novel liposomal formulation of alendronate at the time of PCI with drug-eluting stents failed to reduce restenosis at 9 months in patients with diabetes enrolled in the BLADE-PCI trial.

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September 28, 2019
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EXCEL: PCI ‘acceptable revascularization modality’ for left main CAD at 5 years

EXCEL: PCI ‘acceptable revascularization modality’ for left main CAD at 5 years

SAN FRANCISCO — Final 5-year data from the EXCEL trial demonstrate similar rates of death, stroke or MI with PCI or CABG for treatment of patients with left main CAD, according to late-breaking data presented at TCT 2019.

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September 27, 2019
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PAD Awareness Month: Five recent updates

PAD Awareness Month: Five recent updates

In recognition of Peripheral Artery Disease Awareness Month in September, Healio has compiled a list of five recent updates on PAD.

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September 26, 2019
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MODEL U-SES: 3-month DAPT noninferior to standard DAPT after PCI with bioresorbable SES

MODEL U-SES: 3-month DAPT noninferior to standard DAPT after PCI with bioresorbable SES

SAN FRANCISCO — Among patients who underwent PCI with a bioresorbable polymer sirolimus-eluting stent, 3-month dual antiplatelet therapy was noninferior to longer DAPT, according to results from the MODEL U-SES study.

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September 26, 2019
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Durable-polymer DES noninferior to polymer-free DCS in patients with high bleeding risk, shorter DAPT: Onyx ONE

Durable-polymer DES noninferior to polymer-free DCS in patients with high bleeding risk, shorter DAPT: Onyx ONE

SAN FRANCISCO — In the first randomized trial to compare a durable-polymer DES with a polymer-free drug-coated stent in patients with high bleeding risk who received 1 month of dual antiplatelet therapy, treatment with the DES was as safe and effective as treatment with the DCS, according to results of the Onyx ONE trial presented at TCT 2019.

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September 26, 2019
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TWILIGHT: Switching to ticagrelor monotherapy 3 months post-PCI lowers bleeding vs. DAPT

TWILIGHT: Switching to ticagrelor monotherapy 3 months post-PCI lowers bleeding vs. DAPT

SAN FRANCISCO — Among patients who had PCI with a drug-eluting stent and were on dual antiplatelet therapy for 3 months, subsequent ticagrelor monotherapy lowered bleeding risk without raising ischemic risk compared with continued DAPT, according to results of the TWILIGHT trial presented at TCT 2019.

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