Doxycycline

A second study has shown that taking a single dose of doxycycline within 3 days of having condomless sex can prevent sexually transmitted infections.

BOSTON — A rapid improvement in severe acne was observed in patients treated with 12 weeks of trifarotene and doxycycline, according to a poster presented at the American Academy of Dermatology Annual Meeting.

In this episode, Cassandra Calabrese, DO, dual-boarded in infectious disease and rheumatology, walks us through when to suspect Bartonella (it’s not always a house cat!), how to diagnose and how to treat.

A week-long regimen of doxycycline was superior to a single-dose of azithromycin for the treatment of rectal chlamydia among men who have sex with men, or MSM, according to study results.

The addition of co-trimoxazole or doxycycline to usual care did not significantly improve time to respiratory hospitalization or death in adults with idiopathic pulmonary fibrosis, according to results of the CleanUP-IPF trial.

The use of doxycycline to treat patients with idiopathic granulomatous mastitis showed promise as a first-line therapy, according to a descriptive case series published in JAMA Dermatology.

In recent years, there has been a trending rise in STDs in the United States, forcing experts to look for alternative prevention strategies. Infectious Disease News asked David C. Harvey, MSW, executive director of the National Coalition of STD Directors, to weigh in on one such strategy — the use of doxycycline as pre-exposure prophylaxis, or PrEP.

Leptospirosis is a bacterial infection produced by spirochetes in the genus Leptospira. Leptospira are aerobic but are difficult to cultivate and take many days to grow. They stain poorly with Gram’s stain and are best visualized with silver stain, dark field microscopy or fluorescent microscopy.

Patients with lupus should avoid combined oral contraceptive pills and tetracycline-class medications for acne, whereas isotretinoin and spironolactone may be considered safe treatment options, according to a systematic review.

Findings from a state-of-the-art review showed that doxycycline prophylaxis may be a promising strategy to prevent bacterial STIs.