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Double-Blind Method

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November 19, 2019
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Tofacitinib bested placebo for disease flares in polyarticular JIA

ATLANTA — Results of a double-blind, randomized, placebo-controlled trial showed a clear benefit of tofacitinib in controlling disease flares in juvenile idiopathic arthritis, according to a speaker at ACR/ARP 2019.

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October 24, 2019
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Doctors' expectations of treatment efficacy may alter patient reaction to treatment

Health care providers’ expectations for the effectiveness of a treatment may affect clinical interactions and engender a “socially transmitted placebo effect,” according to results of a study published in Nature Human Behaviour that simulated a clinical interaction.

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September 30, 2019
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Dark chocolate not shown to benefit retinal blood flow, visual function vs. milk chocolate

Study participants who consumed flavanol-rich dark chocolate experienced no beneficial effects in retinal perfusion or visual function compared with those who consumed milk chocolate.

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August 26, 2019
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FDA expands Taltz approval for ankylosing spondylitis

The FDA has extended approval for ixekizumab injection 80 mg/mL to treat adults with ankylosing spondylitis – or radiographic axial spondyloarthritis - according to an Eli Lilly press release.

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August 08, 2019
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FDA accepts NDA for tazarotene lotion for acne

The FDA has accepted a new drug application for IDP-123, a lotion for the treatment of acne, according to an announcement from Bausch Health and Ortho Dermatologics, Bausch’s dermatology business.

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August 07, 2019
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Ingenol mebutate gel 0.027% effective for larger areas of actinic keratosis

Ingenol mebutate gel 0.027% was superior to vehicle treatment for actinic keratosis on the face, scalp and chest with areas 250 cm2.