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June 18, 2021
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Biofilms may be ‘tipping point’ in development of dysbiosis, disease in IBS, UC

Biofilms may be ‘tipping point’ in development of dysbiosis, disease in IBS, UC

Mucosal biofilms are endoscopic features in patients with irritable bowel syndrome and ulcerative colitis with disrupted bile acid metabolism and bacterial dysbiosis, according to a study in Gastroenterology.

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January 19, 2021
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Clinicians should personalize their approach to the management of kidney disease

Clinicians should personalize their approach to the management of kidney disease

As nephrologists know, the decline in kidney function is almost always a “silent disease,” and even patients who experience fatigue and low energy often attribute these symptoms to “getting old,” rather than as signs of illness.

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May 05, 2020
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Sight restoration foundation will help improve outcomes for severe ocular surface disease

Sight restoration foundation will help improve outcomes for severe ocular surface disease

The newly formed Holland Foundation for Sight Restoration will begin funding positions and providing corneal specialists with the tools they need to integrate a treatment protocol for severe ocular surface failure into future centers of excellence across the country.

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April 28, 2020
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Suprachoroidal triamcinolone acetonide improves vision in patients with macular edema

Suprachoroidal triamcinolone acetonide improves vision in patients with macular edema

Patients with macular edema secondary to noninfectious uveitis who were treated with suprachoroidally injected triamcinolone acetonide gained significantly more vision when compared with a sham-treated cohort.

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March 27, 2020
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Q&A: Endoscopists need to prioritize health screenings, procedures during COVID-19 pandemic

With the COVID-19 pandemic, many patients’ previously scheduled health screenings such as cancer screenings and colonoscopies are now being canceled or postponed until further notice. Many centers are prioritizing patients’ procedures as urgent or not.

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March 17, 2020
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Clinical manifestations of COVID-19 appear to be less severe in children

Newly published study findings showed that children are susceptible to COVID-19, but generally have less severe symptoms than adults.

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March 04, 2020
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Targeted treatments extend survival in pancreatic cancer

Targeted treatments extend survival in pancreatic cancer

A precision medicine approach to therapy significantly extended survival for patients with pancreatic cancer compared with standard chemotherapy, according to results of a retrospective study published in The Lancet Oncology.

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February 18, 2020
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Are people with Cushing’s disease refractory to surgery and radiotherapy better served with long-term pharmacotherapy or bilateral adrenalectomy?

Are people with Cushing’s disease refractory to surgery and radiotherapy better served with long-term pharmacotherapy or bilateral adrenalectomy?

The Endocrine Society recommends medical management with a moderate level of evidence; in particular, steroidogenesis inhibitors as a second-line treatment after surgery for people with Cushing’s disease, either with or without radiotherapy, and as primary treatment for ectopic adrenocorticotropic hormone (ACTH) secretion. The guideline also recommends pituitary-directed medical treatments for patients who are not surgical candidates or who have persistent disease after surgery. The choice of medical therapy should be guided by efficacy, individual patient factors and cost.

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January 20, 2020
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Obesity linked to worse psychosocial outcomes among patients with breast, prostate cancer

The physical symptoms of cancer often are accompanied by equally profound psychosocial struggles.

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November 25, 2019
4 min read
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Specific Peptide-Enhanced Affinity Receptor MAGE-A4 T Cells for Synovial Sarcoma

Specific Peptide-Enhanced Affinity Receptor MAGE-A4 T Cells for Synovial Sarcoma

Soft tissue sarcoma is a rare type of cancer that affects the body’s soft tissues, such as muscles, fat and ligaments. There are more than 50 types of soft tissue sarcoma, including synovial sarcoma, which accounts for 5% to 10% of all soft tissue tumors diagnosed each year.

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