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Dipeptidyl-Peptidase IV Inhibitor

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August 12, 2024
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GLP-1 use tied to lower risk for hyperkalemia than DPP-IV therapy in type 2 diabetes

GLP-1 use tied to lower risk for hyperkalemia than DPP-IV therapy in type 2 diabetes

Adults with type 2 diabetes using a GLP-1 receptor agonist are less likely to develop hyperkalemia than those using a DPP-IV inhibitor, according to a study published in JAMA Internal Medicine.

Clinical Guidance
Type 2 Diabetes
Pharmacologic Intervention

Dipeptidyl Peptidase-4

Steven V. Edelman, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

Clinical Guidance
Type 2 Diabetes
Pharmacologic Intervention

Oral Agents

Steven V. Edelman, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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July 29, 2024
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DPP-IV, SGLT2 and GLP-1 drugs do not increase risk for diabetic macular edema

DPP-IV, SGLT2 and GLP-1 drugs do not increase risk for diabetic macular edema

Use of a DPP-IV inhibitor, SGLT2 inhibitor or GLP-1 receptor agonist does not increase risk for diabetic macular edema among adults with type 2 diabetes and diabetic retinopathy, according to study data.

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May 03, 2024
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GLP-1 receptor agonist tied to similar thyroid cancer risk as DPP-IV, SGLT2 inhibitors

GLP-1 receptor agonist tied to similar thyroid cancer risk as DPP-IV, SGLT2 inhibitors

Adults who initiate a GLP-1 receptor agonist have a similar risk for developing thyroid cancer as those prescribed a DPP-IV inhibitor or an SGLT2 inhibitor, according to study findings published in The BMJ.

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April 22, 2024
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Diabetes drugs helping to drive rise in US medication expenditures

Diabetes drugs helping to drive rise in US medication expenditures

Annual expenditures for diabetes medications more than tripled in the U.S. from 2011 to 2020, and the increase played a role in an overall rise in money spent on prescription drugs, according to study findings.

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September 28, 2023
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For older adults with diabetes, CV risk lower with SGLT2 or GLP-1 vs. DPP-IV therapy

For older adults with diabetes, CV risk lower with SGLT2 or GLP-1 vs. DPP-IV therapy

Older adults with type 2 diabetes are less likely to have a cardiovascular event if they are initially prescribed an SGLT2 inhibitor or GLP-1 receptor agonist instead of a DPP-IV inhibitor, according to findings published in Diabetes Care.

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August 17, 2023
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SGLT2 inhibitors preferred for adults with type 2 diabetes and heart failure

SGLT2 inhibitors preferred for adults with type 2 diabetes and heart failure

HOUSTON — SGLT2 inhibitors should be the first choice of therapy for adults with type 2 diabetes and heart failure, according to two speakers at the Association of Diabetes Care and Education Specialists annual meeting.

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January 19, 2023
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Meeting target HbA1c may improve NAFLD for adults with type 2 diabetes

Meeting target HbA1c may improve NAFLD for adults with type 2 diabetes

Adults with type 2 diabetes may be able to reduce their liver fat and improve their liver fibrosis stage with reductions in HbA1c, according to a study published in Nutrition, Metabolism & Cardiovascular Diseases.

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December 06, 2022
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GLP-1 receptor agonist use for more than 1 year may increase thyroid cancer risk

GLP-1 receptor agonist use for more than 1 year may increase thyroid cancer risk

Adults with type 2 diabetes who use a GLP-1 receptor agonist for more than 1 year may have an increased risk for thyroid cancer, according to findings published in Diabetes Care.

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