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June 14, 2024
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Prenatal metformin exposure not tied to long-term adverse childhood neurodevelopment

Prenatal metformin exposure not tied to long-term adverse childhood neurodevelopment

Metformin exposure during pregnancy was not associated with adverse childhood neurodevelopmental outcomes up to age 14 years, according to a systematic review and meta-analysis published in the American Journal of Obstetrics and Gynecology.

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June 14, 2024
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Aim to lower cardiometabolic disease risk when considering dietary pattern for obesity

Aim to lower cardiometabolic disease risk when considering dietary pattern for obesity

PHILADELPHIA — Some dietary change may improve cardiometabolic measures beyond weight loss and providers should create a diet that will most benefit each individual with obesity, according to a speaker.

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June 13, 2024
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‘This is going to take all of us’: Creative partnerships can reduce cardiometabolic risk

‘This is going to take all of us’: Creative partnerships can reduce cardiometabolic risk

BOSTON — Lowering cardiovascular risk for people with type 2 diabetes requires effort from far beyond the clinician’s office, leveraging creative community partnerships that address social determinants of health, according to a speaker.

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June 13, 2024
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New data unraveling role of the gut microbiome in PCOS

New data unraveling role of the gut microbiome in PCOS

BOSTON — Evidence suggests hyperandrogenism is associated with changes in the gut microbiome in women with polycystic ovary syndrome and the gut microbiome may play a causal role in PCOS metabolic dysregulation, according to a speaker.

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June 12, 2024
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Relacorilant tied to sustained cardiometabolic improvements in Cushing’s syndrome

Relacorilant tied to sustained cardiometabolic improvements in Cushing’s syndrome

PHILADELPHIA — Adults with Cushing’s syndrome who responded to relacorilant had sustained improvements in blood pressure and glucose levels through 34 weeks, according to findings from a phase 3 trial.

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June 11, 2024
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Preemptive kidney transplant in older adults linked to better patient, graft survival

Preemptive kidney transplant in older adults linked to better patient, graft survival

PHILADELPHIA — Preemptive kidney transplant in older adults with a high kidney donor profile index pre-transplant may be linked to better patient and graft survival, data show.

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June 11, 2024
3 min read
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Elevated risk from diabetes in acute MI, PCI cohort not due to plaque composition

Elevated risk from diabetes in acute MI, PCI cohort not due to plaque composition

PHILADELPHIA — In patients with acute MI who had successful PCI and underwent imaging to assess plaque composition, diabetes raised risk for poor outcomes but the difference was not related to plaque, according to a presentation.

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June 11, 2024
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Two-step screening could prevent heart failure in diabetes with no history of CVD

Two-step screening could prevent heart failure in diabetes with no history of CVD

PHILADELPHIA — Early, cost-effective screening may predict and prevent incident heart failure events for patients with diabetes and no prior heart disease, a speaker reported.

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June 11, 2024
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Osilodrostat improves comorbid hypertension, diabetes for adults with Cushing’s disease

Osilodrostat improves comorbid hypertension, diabetes for adults with Cushing’s disease

BOSTON — Long-term osilodrostat therapy may improve symptoms of comorbid cardiometabolic disorders such as hypertension and diabetes for adults with Cushing’s disease, according to data presented at ENDO 2024.

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June 10, 2024
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Low eGFR linked to high mortality rate but not to cardiovascular events in older patients

Low eGFR linked to high mortality rate but not to cardiovascular events in older patients

Among older adults participating in the Systolic Blood Pressure Intervention Trial, a low eGFR without albuminuria was associated with a higher mortality rate but not with increased risk of cardiovascular events, results showed.

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