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Dermatomyositis

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September 09, 2024
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FDA grants rare pediatric disease designation to Descartes-08 for juvenile dermatomyositis

FDA grants rare pediatric disease designation to Descartes-08 for juvenile dermatomyositis

The FDA has granted rare pediatric disease designation to Descartes-08, an autologous mRNA cell therapy, for the treatment of juvenile dermatomyositis, Cartesian Therapeutics announced in a press release.

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July 30, 2024
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Phase 3 enrollment completed for study evaluating brepocitinib in dermatomyositis

Phase 3 enrollment completed for study evaluating brepocitinib in dermatomyositis

Enrollment in the phase 3 VALOR study evaluating brepocitinib for the treatment of dermatomyositis has been completed, Priovant Therapeutics announced in a press release.

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July 19, 2024
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Lung involvement, cancer ‘two things you should always worry about’ in dermatomyositis

Lung involvement, cancer ‘two things you should always worry about’ in dermatomyositis

ORLANDO, Fla. — Malignancies and lung involvement are the two key manifestations of dermatomyositis that require vigilance, according to a presenter at the 2024 Rheumatology Nurses Society annual conference.

News
June 01, 2024
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VIDEO: ‘Future has never looked brighter’ in treating dermatomyositis

VIDEO: ‘Future has never looked brighter’ in treating dermatomyositis

CLEVELAND — Dermatomyositis treatment options could grow exponentially in the next few years, according to David Fiorentino, MD, PhD, professor of dermatology at Stanford University.

News
May 11, 2024
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'Full cancer screening' essential for patients of all ages with dermatomyositis

'Full cancer screening' essential for patients of all ages with dermatomyositis

DESTIN, Fla. — Although the strongest predictor of malignancy in dermatomyositis is age, all adult patients should undergo cancer screening, according to a speaker at the Congress of Clinical Rheumatology East annual meeting.

News
May 16, 2023
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FDA clears way for CAR T-cell therapy trial in patients with myositis

FDA clears way for CAR T-cell therapy trial in patients with myositis

The FDA has granted an investigational new drug application for CABA-201, a 4-1BB-containing fully human CD19-CAR T-cell therapy, to be studied in patients with myositis, according to a press release from the manufacturer.

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May 09, 2023
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‘Exciting time for myositis’: Drug pipeline shifts from organ-centric to targeted therapy

‘Exciting time for myositis’: Drug pipeline shifts from organ-centric to targeted therapy

DESTIN, Fla. — Although new targets and therapies are on the horizon, current myositis treatment strategies rely on treating impacted organ groups, according to a speaker at the 2023 Congress of Clinical Rheumatology-East.

News
May 07, 2023
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Cutaneous complications offer ‘lots of mimickers’ for rheumatologic diseases

DESTIN, Fla. — Dermatomyositis and tinea are just two of many dermatologic complications that may resemble rheumatologic conditions, according to a presenter at the 2023 Congress of Clinical Rheumatology-East.

News
November 12, 2022
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Dermatomyositis among high risk factors for cancer in idiopathic inflammatory myopathy

Dermatomyositis among high risk factors for cancer in idiopathic inflammatory myopathy

PHILADELPHIA — High risk factors for cancer in patients with idiopathic inflammatory myopathy include dermatomyositis, anti-TIF1-gamma positivity, anti-NXP2 positivity and age 40 or older at onset, said a speaker here.

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November 11, 2022
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Apremilast may be safe, efficacious option in recalcitrant cutaneous dermatomyositis

Apremilast may be safe, efficacious option in recalcitrant cutaneous dermatomyositis

Apremilast may be an efficacious and safe treatment option for patients with recalcitrant cutaneous dermatomyositis, according to a study.

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