Darier Disease

Second-hit somatic variants in the ATP2A2 gene were associated with persistent Darier disease lesions, according to a case series study.

Grover’s disease may be associated with damaging single-nucleotide variants in the ATP2A2 gene, highlighting the role of somatic variation in acquired disorders, according to a study.

Prolonged use of systemic retinoids was safe and effective for the treatment of patients with moderate to severe Darier disease, according to study results presented at the American Academy of Dermatology virtual meeting.