Cortisol
DHEAS may serve as biomarker for diagnosing adrenal insufficiency
The use of dehydroepiandrosterone sulfate to determine an adrenal insufficiency diagnosis has similar accuracy to using baseline cortisol level, according to findings published in The Journal of Clinical Endocrinology & Metabolism.
Inhaled corticosteroids for asthma may increase risk for adrenal suppression
SAN DIEGO — Plasma metabolite profiles were significantly associated with cortisol levels among patients with asthma who use inhaled corticosteroids, according to a poster at the American Thoracic Society International Conference.
Bone quality may improve after adrenalectomy for mild autonomous cortisol secretion
NEW ORLEANS —A small group of adults with mild autonomous cortisol secretion had an increase in spine trabecular bone score following adrenalectomy, according to a speaker at the AACE annual meeting.
Adults diagnosed with mild autonomous cortisol secretion more likely to develop CKD
Adults with mild autonomous cortisol secretion are more likely to have advanced chronic kidney disease at adrenal adenoma diagnosis than adults with a nonfunctioning adrenal adenoma, according to study data.
LYT-300 achieves statistically significant stress hormone reduction in phase 2a trial
LYT-300, a therapeutic for anxiety disorders, has achieved topline results in a phase 2a, randomized, placebo-controlled, proof-of-concept trial, the manufacturer announced in a press release.
Adults diagnosed with adrenocortical cancer have 54% overall survival at 5 years
Adults who are diagnosed with adrenocortical cancer have a 5-year overall survival of 54%, with overall survival higher among those with stage I or stage II cancer, according to study findings.
Cortisol levels in last trimester may predict infant sleep onset at 7 months
INDIANAPOLIS — Newborns with higher levels of hair cortisol, a measure of fetal cortisol in the last trimester of pregnancy, were more likely to have delayed sleep onset at age 7 months, according to preliminary research.
Cortisone levels measured in scalp hair may predict future CVD risk
Adults with higher cortisone levels as measured in their scalp hair may be more likely to develop future cardiovascular disease, according to a presenter at the European Congress on Obesity.
Cushing’s syndrome treatment maintains reductions in urinary free cortisol for 12 months
Most adults with Cushing’s syndrome receiving levoketoconazole twice daily maintained reductions in mean urinary free cortisol levels during a 12-month maintenance period, according to findings from the SONICS study extended evaluation.
Osilodrostat normalizes urinary free cortisol in Cushing’s disease for most at 72 weeks
More than 80% of adults with Cushing’s disease receiving osilodrostat had normalized mean urinary free cortisol levels at 72 weeks of treatment, according to findings from the LINC 3 study extension.