Corticosteroid

Combining the corticosteroid fluocinolone acetonide with ciprofloxacin was safe and efficacious in treating swimmer’s ear, although it was not superior to treatment with either agent alone, according to a study published in JAMA Network Open.

Intranasal corticosteroid and intranasal antihistamine therapies did a better job of alleviating nasal and ocular symptoms in allergic rhinitis than intranasal corticosteroid therapy alone, according to a review.

Cumulative exposure to glucocorticoids appeared associated with risk for adrenal insufficiency among patients with severe asthma, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

Kala Pharmaceuticals has entered into a definitive agreement to sell its commercial portfolio and related assets to Alcon, including Eysuvis and Inveltys.

SAN DIEGO — Corticosteroid use should be minimized in patients with inflammatory bowel disease to reduce the risk for invasive fungal infections, according to research presented at Digestive Disease Week 2022.

SAN DIEGO — Baseline magnetic resonance index of activity score independently predicted the longer-term need for surgery, rescue corticosteroids or hospitalizations among patients with Crohn’s disease.

SAN FRANCISCO — In patients with uncontrolled moderate to severe asthma, a fixed-dose combination of albuterol and budesonide used as an as-needed rescue medication lowered risk for severe asthma exacerbations compared with albuterol alone.

The pro-inflammatory protein IL-3 appeared to regulate the burden of allergic asthma by inducing T regulatory cell response and reducing the proliferation of type 2 innate lymphoid cells, according to a study in Frontiers in Immunology.

Although infrequent, high use of short-acting beta 2 agonists was associated with more severe asthma, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

Exposure to systemic corticosteroids appeared to increase risk for hospitalization for vaso-occlusive episodes among patients with sickle cell disease, according to a French study published in Blood.