Coronary Artery Disease

Adults with type 2 diabetes may be at higher risk for major adverse cardiovascular events, coronary artery disease and other cardiometabolic disorders if they consistently experience large changes in HbA1c, according to findings published in Diabetes Care.

PHILADELPHIA — Interim data using coronary CT angiography demonstrated benefits of icosapent ethyl as an adjunct to statin therapy on several plaque characteristics at 9 months in adults with high triglycerides and coronary atherosclerosis.

PHILADELPHIA — In an OCT substudy of the COMPLETE trial, researchers determined that 47% of patients had obstructive nonculprit lesions with vulnerable plaque, which could explain why complete revascularization conferred better outcomes than culprit lesion-only revascularization in the main trial.

Patients who underwent noninvasive diagnostic testing after evaluation for chest pain in the ED had a lower observed rate of CV death or MI, according to a retrospective cohort study published in the Journal of the American Heart Association.

SAN FRANCISCO — Guidance with OCT led to a lower occurrence of significant angina or the composite of MACE compared with guidance with fractional flow reserve in patients with angiographically intermediate coronary lesions, according to 13-month data from the FORZA trial presented at TCT 2019.

Adults with a history of juvenile arthritis carry a greater risk for coronary artery disease compared with those without arthritis, according to data published in Arthritis Care & Research.

SAN FRANCISCO — Orbital and rotational atherectomy conferred similar outcomes in patients with calcified CAD who underwent PCI, according to the results of a retrospective cohort study presented at TCT 2019.

SAN FRANCISCO — Among patients with three-vessel disease who underwent PCI, achievement of a quantitative flow ratio of at least 0.91 in all treated vessels was associated with improved vessel-related outcomes, according to findings presented at TCT 2019.

In the U.S., changes in household income were significantly associated with subsequent incident CVD, with a strong link between drop in income and risk for CVD, according to a study published in JAMA Cardiology.

SAN FRANCISCO — An intravascular lithotripsy device used for vessel preparation for stenting in patients with severely calcified coronary lesions was safe and effective, according to results from the DISRUPT CAD II study presented at TCT 2019.