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Coronary Artery Disease

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March 28, 2020
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Genotype-guided antiplatelet therapy strategy shows benefit after PCI

Genotype-guided antiplatelet therapy strategy shows benefit after PCI

While not meeting a performance goal, genetic screening of patients with ACS or stable CAD after PCI to guide antiplatelet therapy choice numerically reduced serious adverse CV events, according to the results of the TAILOR PCI trial.

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March 24, 2020
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In new-onset HF, rate of CAD testing lower than expected

In new-onset HF, rate of CAD testing lower than expected

Fewer than half of patients with new-onset HF are tested for CAD, and even fewer are tested during their index hospitalization.

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March 19, 2020
11 min read
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Genetic risk score could revolutionize primary prevention of CAD

Genetic risk score could revolutionize primary prevention of CAD

CAD, despite the success of secondary prevention, is pandemic and the leading cause of death in high-, middle- and low-income countries throughout the world.

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February 18, 2020
4 min read
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Clinical utility of polygenic risk scores for CHD, CAD questioned

Clinical utility of polygenic risk scores for CHD, CAD questioned

Two polygenic risk scores, one for predicting CHD and one for predicting CAD, did not meaningfully improve risk prediction beyond conventional risk factors, according to findings published in JAMA.

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February 17, 2020
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BASEL VIII

BASEL VIII

Electrocardiographic and biochemical signatures with ECG or alone to detect exercise-induced myocardial ischemia in patients with CAD.

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February 14, 2020
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Over 13 years, mortality declined after CABG, but not after PCI

Over 13 years, mortality declined after CABG, but not after PCI

Among patients who underwent PCI or CABG between 2003 and 2016, risk-adjusted mortality decreased in the CABG population but not in the PCI population over time, researchers reported in JAMA Network Open.

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February 13, 2020
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Greater immature platelet fraction reduces CAD risk, but ‘no difference’ for blood glucose

Greater immature platelet fraction reduces CAD risk, but ‘no difference’ for blood glucose

The risk for coronary artery disease may be lower among those with diabetes who have elevated vs. lower immature platelet fraction, although glucose management is unaffected by this biomarker, according to findings published in Diabetes/Metabolism Research and Reviews.

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January 22, 2020
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Rising HbA1c levels contribute to CV event risk in diabetes, CAD

Rising HbA1c levels contribute to CV event risk in diabetes, CAD

The longitudinal increase of HbA1c was found to be independently associated with elevated incidence of CV events for patients with diabetes and multivessel CAD, according to findings published in JAMA Network Open.

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January 13, 2020
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FFR may confer treatment reclassification in CAD, diabetes

FFR may confer treatment reclassification in CAD, diabetes

Routine use of fractional flow reserve to manage CAD among patients with diabetes may be linked to an increased rate of treatment reclassification, according to a study published in JAMA Cardiology.

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January 06, 2020
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High-sensitivity cardiac troponin may not exclude myocardial ischemia

High-sensitivity cardiac troponin may not exclude myocardial ischemia

Very low concentrations of high-sensitivity cardiac troponin did not allow the safe exclusion of inducible myocardial ischemia, according to a study published in the Annals of Internal Medicine.

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