Congenital Heart Disease

U.S. adults of low socioeconomic status experienced double the incidence of MI and CHD-related deaths than individuals of higher status, but less than half of excess events were attributable to traditional risk factors.

Women who used oral fluconazole — a common treatment for vulvovaginal candidiasis — during the first trimester of pregnancy were more likely to give birth to an infant with musculoskeletal malformations, but not oral clefts or conotruncal malformations, which were previously linked to the medication, according to a study published in BMJ.

Social deprivation and environmental pollutant exposure are potential risk factors for live-born congenital heart disease in California, indicating that harmful toxins may be prevalent in at-risk communities, researchers reported.

Eating higher quantities of tofu and isoflavones lowers the risk for CHD, especially in young women or postmenopausal women who do not use hormones, according to a study published in Circulation.

Two polygenic risk scores, one for predicting CHD and one for predicting CAD, did not meaningfully improve risk prediction beyond conventional risk factors, according to findings published in JAMA.

The risk for congenital heart disease-related infant mortality was higher when mothers lived farther from specialized pediatric cardiac centers, according to a research letter published in Circulation.

A recent study published in the Annals of Thoracic Surgery found that cardiac allografts from high-risk donors implanted in children resulted in similar posttransplant survival as those from low-risk donors.

Artificial intelligence-based analysis of chest X-rays was able to successfully predict the pulmonary to systemic flow ratio in patients with congenital heart disease with greater efficacy than trained pediatric cardiologists, according to findings published in JAMA Cardiology.

Among patients with non-ST-segment elevation ACS undergoing coronary angiography who were pretreated with clopidogrel, those using morphine had higher ischemic event rates compared with nonusers, according to new data from the EARLY ACS trial.

Psychological distress in women carrying fetuses with congenital heart disease, or CHD, is associated with impaired cerebellar and hippocampal development during the second half of gestation, according to results from a study published in JAMA Pediatrics.