Colorectal Liver Metastases

Hepatic arterial infusion pump (HAIP) chemotherapy, developed in the 1980s, has shown efficacy as an advanced treatment option for primary and secondary hepatic malignancies.

The International Hepato-Pancreato-Biliary Association established consensus guidelines for liver transplantation among patients with nonresectable colorectal liver metastases.

Laparoscopic surgery appeared as effective as open surgery among patients with colorectal liver metastases, according to long-term results of the randomized, phase 3 OSLO-COMET trial.

The U.S. Preventive Services Task Force released a draft recommendation expanding colorectal cancer screening to adults aged 45 years. It was the top story in hematology/oncology last week.

Black patients with colorectal liver metastases had a lower likelihood of undergoing chemotherapy or resection and shorter survival than their counterparts of other races and ethnicities, according to a research letter in JAMA Network Open.

Resection of colorectal liver metastases, often performed in conjunction with chemotherapy, can substantially extend survival — a fact that has been acknowledged for about 20 years.

The addition of bevacizumab to modied FOLFOX6 improved liver metastases resection rates and survival outcomes among certain patients with colorectal liver metastases, according to study results published in Journal of Clinical Oncology.

Cetuximab plus chemotherapy resulted in shorter PFS and OS compared with chemotherapy alone among patients with resectable KRAS exon 2 wild-type colorectal liver metastases, according to results of the randomized phase 3 New EPOC study published in Lancet Oncology.

Patients who undergo primary tumor resection as an initial treatment for synchronous colorectal liver metastases are at increased risk for progressive disease, according to data presented at the American Society of Colon and Rectal Surgeons Annual Meeting in Phoenix.