Colorectal Cancer

An alkylating mutational signature in colon cells appeared to be associated with red meat consumption and certain cancer driver mutations, according to a recent study. An interview with one of the authors was the top story in hematology/oncology last week.

Researchers have identified a possible molecular link between high consumption of both processed and unprocessed red meat and increased colorectal cancer risk and mortality.

Compared with other patients with breast cancer, those with HR–/HER2+ breast cancer have increased rates of brain metastases, according to research presented at ASCO 2021.

Gastric cancer populations that show higher rates of phosphorylated signal transducer and activator of transcription 3 were more likely to have a shorter medial overall survival rate , according to data from a three phase 3 clinical trials presented at ASCO.

Though clinical guidelines specify that oncologists should talk with patients about the risks for treatment-induced infertility, many patients with colon and rectal cancer report they did not receive or do not remember receiving information from their health care providers, according to a presentation at ASCO21 Annual Meeting.

Black veterans had a higher prevalence of advanced colorectal neoplasia and colorectal cancer compared with white veterans, according to research published in the Journal of Clinical Gastroenterology.

Fecal immunochemical test improved the efficiency of referrals in patients with new-onset lower gastrointestinal symptoms within a primary health care setting, according to research published in Gut.

Healio Gastroenterology presents the following reports on the top peer-tested stories in May.

Liquid biopsy-driven rechallenge with panitumumab led to objective responses in about one-third of patients with metastatic colorectal cancer, according to results of the phase 2 CHRONOS study presented at the virtual ASCO Annual Meeting.

The occurrence of colorectal cancer in colonoscopies performed on patients aged between 45 and 50 years showed rates that approach those in ages 50 to 54 years, according to a presentation at Digestive Diseases Week.