Colorectal Cancer
FDA clears IND application for CAR-T to treat metastatic colorectal cancer
The FDA cleared an investigational new drug application for GCC19CART, a chimeric antigen receptor T-cell therapy designed to treat patients with relapsed or refractory metastatic colorectal cancer.
Use of antibiotics linked to increased risk for proximal colon cancer
Use of antibiotics appeared consistently associated with higher subsequent risk for proximal colon cancer, according to results of a nationwide, population-based study published in Journal of the National Cancer Institute.
Most patients do not have an endoscopist sex preference
Patients were more likely to express preference for a same-sex endoscopy team member than a same-sex endoscopist, according to survey results published in the American Journal of Gastroenterology.
Maternal obesity, weight gain increase risk for CRC among adult offspring
In utero events such as maternal obesity and weight gain increased the risk for colorectal cancer development among adult offspring, according to research published in Gut.
Early-onset colorectal cancer may not be biologically different from average-onset disease
Early-onset colorectal cancer did not appear genomically distinct from average-onset disease, according to results of a retrospective, single-institution analysis published in Journal of the National Cancer Institute.
Higher vitamin D intake may decrease risk for CRC
Higher intake of vitamin D correlated with a decreased risk for early-onset colorectal cancer and CRC precursors among a cohort of young women, according to research published in Gastroenterology.
Q&A: Multitarget FIT bests regular FIT in adenoma detection
Multitarget fecal immunochemical testing yielded better diagnostic accuracy in the detection of advanced adenomas compared with basic FIT, according to research published in Annals of Internal Medicine.
AGA publishes clinical practice update on chemoprevention of colorectal neoplasia
The American Gastroenterological Association published a clinical practice update to describe the role of medications for the chemoprevention of colorectal neoplasia.