Colorectal Cancer

Increased incidence of early-onset colorectal cancer and precancerous polyp diagnoses among patients at a younger age supported the recommendation for CRC screening at age 45 for all average risk individuals, according to a study.

Younger and older patients with metastatic colorectal cancer had similar survival outcomes despite differences in fitness levels and treatment intensity, according to study results published in Journal of the National Cancer Institute.

Since the start of the COVID-19 pandemic, many patients have not received preventive care, and “it is vital that they get caught up now,” the chair of the U.S. Preventive Services Task Force told Healio Primary Care.

About one in four primary care clinicians surveyed preferred a stool-based test to a colonoscopy for colorectal cancer screening, according to findings published in Mayo Clinic Proceedings.

Sotorasib demonstrated antitumor activity among patients with heavily pretreated advanced KRAS G12C-mutated colorectal cancer, according to results of the phase 2 CodeBreak 100 trial published in The Lancet Oncology.

Healio Gastroenterology presents the following report on the top 10 peer-tested articles from November 2021.

The protective effect of a single flexible sigmoidoscopy screening in older adults was maintained for up 15 years against colorectal cancer incidence and for up to 19 years against mortality, according to a randomized controlled trial.

The FDA granted fast track designation to arfolitixorin for treatment of patients with metastatic colorectal cancer.

A recent study showed that most cancer therapies tested in phase 3 trials lack survival benefits, prompting researchers to advocate for more stringent criteria to determine which therapies should advance to phase 3 development.

The U.S. Multi-Society Task Force on Colorectal Cancer updated its screening recommendations.